Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 3/20 | 0.47 |
| ▸ | NOS3 | P29474 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4568906 | 0.84 | MAPK1 (0.50) | BCHEKDM4E | |
| SCHEMBL13881720 | 0.83 | CHRM2 (0.48) | NOS1BCHEMEN1KMT2A | |
| SCHEMBL3964848 | 0.83 | CYP4F2 (0.44) | BCHE | |
| SCHEMBL13881943 | 0.82 | KDM4E (0.54) | KDM4EPRMT5WDR77MEN1KMT2A | |
| SCHEMBL4569157 | 0.82 | BCHE (0.40) | BCHEKDM4EPRMT5WDR77MEN1 | |
| SCHEMBL10278756 | 0.82 | EPHX2 (0.40) | BCHEPRMT5WDR77MEN1KMT2A | |
| SCHEMBL19291786 | 0.82 | KDM4E (0.54) | KDM4EPRMT5WDR77MEN1KMT2A | |
| SCHEMBL2205362 | 0.82 | MAOB (0.48) | NOS1BCHE | |
| SCHEMBL4568761 | 0.81 | PPARA (0.51) | BCHE | |
| SCHEMBL19291579 | 0.79 | HTR1B (0.51) | KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ALDH1A2, CLN6, AGER | NOS1 1659/4885NOS3 1001/4885BCHE 1649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.