Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | TK2 | O00142 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CDA | P32320 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6130423 | 0.79 | CDA (0.53) | CDA | |
| SCHEMBL7873609 | 0.75 | TK1 (0.40) | TK1LMNASMN1; SMN2ALOX12ADRA1A | |
| SCHEMBL5982761 | 0.74 | TK1 (0.43) | TK1LMNASMN1; SMN2ALOX12ADRA1A | |
| SCHEMBL6026652 | 0.74 | TK1 (0.43) | TK1LMNASMN1; SMN2ALOX12ADRA1A | |
| SCHEMBL8600466 | 0.74 | TK1 (0.43) | TK1LMNASMN1; SMN2ALOX12ADRA1A | |
| SCHEMBL7148871 | 0.74 | TK1 (0.41) | TK1LMNASMN1; SMN2ALOX12ADRA1A | |
| SCHEMBL7148864 | 0.74 | TK1 (0.41) | TK1LMNASMN1; SMN2ALOX12ADRA1A | |
| SCHEMBL15893325 | 0.74 | CDA (0.58) | TK1LMNASMN1; SMN2ALOX12ADRA1A | |
| SCHEMBL658757 | 0.74 | CDA (0.58) | TK1LMNASMN1; SMN2ALOX12ADRA1A | |
| SCHEMBL21423103 | 0.74 | CDA (0.58) | TK1LMNASMN1; SMN2ALOX12ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3046932-A2 | EVOLVED SORTASES AND USES THEREOF | President and Fellows of Harvard College (US) | 2016-07-27 | — | — | EP | disclosed |
| WO-2015042393-A9 | EVOLVED SORTASES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-06-16 | — | — | WO | disclosed |
| WO-2015042393-A2 | EVOLVED SORTASES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-03-26 | — | — | WO | disclosed |
| WO-2012125445-A2 | SMALL MOLECULE-DEPENDENT INTEINS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-09-20 | — | — | WO | disclosed |
| WO-2009043096-A1 | IMPROVED METHOD FOR MUTAGENESIS | ARANA THERAPEUTICS (VIC) PTY LTD (AU) | 2009-04-09 | — | — | WO | disclosed |
| EP-1981992-A2 | PROMOTER ENGINEERING AND GENETIC CONTROL | Massachusetts Institute of Technology (MIT) (US) | 2008-10-22 | — | — | EP | disclosed |
| EP-1691792-A4 | COMPOSITIONS AND METHODS FOR IN VITRO SORTING OF MOLECULAR AND CELLULAR LIBRARIES | YEDA RES & DEV (IL) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007079428-A2 | PROMOTER ENGINEERING AND GENETIC CONTROL | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-07-12 | — | — | WO | disclosed |
| EP-1805324-A2 | IN VITRO EVOLUTION IN MICROFLUIDIC SYSTEMS | Medical Research Council (GB) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006124895-A2 | MUTATIONS FOR ENHANCED TYROSINE PRODUCTION | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2006-11-23 | — | — | WO | disclosed |
| WO-2006116400-A2 | PROMOTER ENGINEERING AND GENETIC CONTROL | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2006-11-02 | — | — | WO | disclosed |
| EP-1691792-A2 | COMPOSITIONS AND METHODS FOR IN VITRO SORTING OF MOLECULAR AND CELLULAR LIBRARIES | YEDA RESEARCH AND DEVELOPMENT Co. LTD. (IL) | 2006-08-23 | — | — | EP | disclosed |
| WO-2006038035-A2 | IN VITRO EVOLUTION IN MICROFLUIDIC SYSTEMS | MEDICAL RESEARCH COUNCIL (GB) | 2006-04-13 | — | — | WO | disclosed |
| WO-2005049787-A9 | COMPOSITIONS AND METHODS FOR IN VITRO SORTING OF MOLECULAR AND CELLULAR LIBRARIES | YEDA RES & DEV (IL) | 2005-06-23 | — | — | WO | disclosed |
| WO-2005049787-A2 | COMPOSITIONS AND METHODS FOR IN VITRO SORTING OF MOLECULAR AND CELLULAR LIBRARIES | YEDA RESEARCH AND DEVELOPMENT CO.LTD. (IL) | 2005-06-02 | — | — | WO | disclosed |
| WO-2002079502-A1 | A METHOD FOR NUCLEIC ACID SEQUENCE ANALYSIS | THE UNIVERSITY OF QUEENSLAND (AU) | 2002-10-10 | — | — | WO | disclosed |
| EP-1165838-A2 | COUPLED POLYMERASE CHAIN REACTION-RESTRICTION ENDONUCLEASE DIGESTION-LIGASE DETECTION REACTION PROCESS | CORNELL RESEARCH FOUNDATION, INC. (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000056929-A2 | COUPLED POLYMERASE CHAIN REACTION-RESTRICTION ENDONUCLEASE DIGESTION-LIGASE DETECTION REACTION PROCESS | CORNELL RESEARCH FOUNDATION, INC. (US) | 2000-09-28 | — | — | WO | disclosed |