⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9587778 | 0.90 | LMNA (0.33) | — | |
| SCHEMBL3218836 | 0.81 | — | — | |
| SCHEMBL16610533 | 0.78 | — | — | |
| SCHEMBL28346370 | 0.76 | — | — | |
| SCHEMBL28433700 | 0.76 | — | — | |
| SCHEMBL17049723 | 0.72 | — | — | |
| SCHEMBL28428341 | 0.71 | — | — | |
| SCHEMBL2538298 | 0.70 | THRB (0.31) | — | |
| SCHEMBL2438517 | 0.70 | — | — | |
| SCHEMBL2688523 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56050545-A | — | — | None | — | — | JP | disclosed |
| JP-8307976-A | — | — | None | — | — | JP | disclosed |
| US-12605469-B2 | Tumor specific antibody conjugates and uses therefor | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE (US) | 2026-04-21 | — | — | US | disclosed |
| US-20260007783-A1 | A 3E8.scFv.Cys-IR800 Conjugate Targeting TAG-72 in an Orthotopic colorectal cancer model | OHIO STATE INNOVATION FOUNDATION (US) | 2026-01-08 | — | — | US | disclosed |
| US-12370273-B2 | 3E8.scFv.Cys-IR800 conjugate targeting TAG-72 in an orthotopic colorectal cancer model | Ohio Sate Innovation Foundation (US) | 2025-07-29 | — | — | US | disclosed |
| US-20240166762-A1 | METHODS AND COMPOSITIONS RELATED TO ANTIBODY FRAGMENTS THAT BIND TO TUMOR-ASSOCIATED GLYCOPROTEIN 72 (TAG-72) | OHIO STATE INNOVATION FOUNDATION (US) | 2024-05-23 | — | — | US | disclosed |
| US-20240108764-A1 | 3E8.scFv.Cys-IR800 Conjugate Targeting TAG-72 in an Orthotopic colorectal cancer model | OHIO STATE INNOVATION FOUNDATION | 2024-04-04 | — | — | US | disclosed |
| US-11787872-B2 | Methods and compositions related to antibody fragments that bind to tumor-associated glycoprotein 72 (TAG-72) | OHIO STATE INNOVATION FOUNDATION (US) | 2023-10-17 | — | — | US | disclosed |
| US-20230049618-A1 | TUMOR SPECIFIC ANTIBODY CONJUGATES AND USES THEREFOR | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE (US) | 2023-02-16 | — | — | US | disclosed |
| US-11554181-B2 | Tumor specific antibody conjugates and uses therefor | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE (US) | 2023-01-17 | — | — | US | disclosed |
| US-20030130190-A1 | In vivo panning for ligands to radiation-induced molecules | VANDERBILT UNIVERSITY | 2003-07-10 | — | — | US | disclosed |
| US-20030127173-A1 | Fixing belt and method for evaluating it | RICOH COMPANY, LTD. (JP) | 2003-07-10 | — | — | US | disclosed |
| EP-0988062-A4 | SELECTIVELY BINDING ULTRASOUND CONTRAST AGENTS | MALLINCKRODT INC (US) | 2003-04-23 | — | — | EP | disclosed |
| WO-2003028640-A2 | IN VIVO PANNING FOR LIGANDS TO RADIATION-INDUCED MOLECULES | VANDERBILT UNIVERSITY (US) | 2003-04-10 | — | — | WO | disclosed |
| US-6245318-B1 | COMPOSITION COMPRISING ULTRASOUND CONTRAST, POLYMERIC SPACER AND LIGAND | MALLINCKRODT INC. | 2001-06-12 | — | — | US | disclosed |
| US-6059719-A | Endoscope system | OLYMPUS OPTICAL CO., LTD. (JP) | 2000-05-09 | — | — | US | disclosed |
| EP-0988062-A1 | SELECTIVELY BINDING ULTRASOUND CONTRAST AGENTS | Mallinckrodt Inc. (US) | 2000-03-29 | — | — | EP | disclosed |
| WO-1998053857-A1 | SELECTIVELY BINDING ULTRASOUND CONTRAST AGENTS | MALLINCKRODT MEDICAL, INC. (US) | 1998-12-03 | — | — | WO | disclosed |
| JP-H08307976-A | STAND FOR SPEAKER CABINET | NIPPON COLUMBIA CO LTD | 1996-11-22 | — | — | JP | disclosed |
| JP-S5650545-A | RESIN MOLDED TYPE SEMICONDUCTOR DEVICE | HITACHI LTD | 1981-05-07 | — | — | JP | disclosed |