Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.46 |
| ▸ | CNR1 | P21554 | 5/20 | 0.46 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4010398 | 0.88 | CNR2 (0.44) | CNR2CNR1FFAR2RORCGAA | |
| SCHEMBL4010397 | 0.87 | CNR2 (0.43) | CNR2CNR1FFAR2RORCGAA | |
| SCHEMBL4017108 | 0.82 | CNR2 (0.44) | CNR2CNR1GAAKDM4EMAPT | |
| SCHEMBL4017105 | 0.81 | CNR2 (0.44) | CNR2CNR1GAAKDM4EMAPT | |
| SCHEMBL4163865 | 0.81 | CNR2 (0.42) | CNR2CNR1FFAR2RORCKDM4E | |
| SCHEMBL1619416 | 0.79 | GRM4 (0.47) | CNR2CNR1FFAR2GAAKDM4E | |
| SCHEMBL4165730 | 0.79 | CNR2 (0.44) | CNR2CNR1 | |
| SCHEMBL1621385 | 0.79 | FFAR2 (0.53) | FFAR2RORCKDM4ENPSR1MAPT | |
| SCHEMBL1621011 | 0.78 | CNR2 (0.70) | CNR2CNR1GAANPSR1MAPT | |
| SCHEMBL4015637 | 0.74 | CNR1 (0.36) | CNR2CNR1FFAR2GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074084-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-01 | — | — | EP | claimed |
| WO-2008039645-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-04-03 | — | — | WO | claimed |