SCHEMBL3965068

SCHEMBL3965068

C=CCc1cc(C)cc(C(=O)O)c1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.41
HMGB1 P09429 2/20 0.41
CXCL12 P48061 2/20 0.41
ALDH1A1 P00352 1/20 0.41
HPGD P15428 1/20 0.41
CSNK2A1 P68400 1/20 0.41
GAA P10253 2/20 0.40
KDM4E B2RXH2 3/20 0.40
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
PTPN1 P18031 4/20 0.38
PTPN2 P17706 2/20 0.38
PTPN6 P29350 2/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
TSHR P16473 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
AKR1C2 P52895 1/20 0.36
AKR1C1 Q04828 1/20 0.36
GABRA1 P14867 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14372980 0.83 GAA (0.41) HSD17B10ALDH1A1HPGDGAAKDM4E
SCHEMBL9332613 0.82 GAA (0.53) GAAKDM4EESR1ESR2MEN1
SCHEMBL9960069 0.81 ALDH1A1 (0.47) HSD17B10HMGB1CXCL12ALDH1A1HPGD
SCHEMBL3364581 0.81 PTPN1 (0.49) HSD17B10HMGB1CXCL12ALDH1A1HPGD
SCHEMBL4074396 0.81 ALDH1A1 (0.42) HSD17B10HMGB1CXCL12ALDH1A1HPGD
SCHEMBL14373013 0.81 HSD17B10 (0.41) HSD17B10ALDH1A1GAAKDM4EMEN1
SCHEMBL14400617 0.81 KDM4E (0.38) HSD17B10ALDH1A1CSNK2A1GAAKDM4E
SCHEMBL14124080 0.80 HSD17B10 (0.61) HSD17B10HMGB1CXCL12ALDH1A1HPGD
SCHEMBL1641608 0.80 HMGB1 (0.47) HSD17B10HMGB1CXCL12ALDH1A1HPGD
SCHEMBL16632831 0.80 HMGB1 (0.41) HSD17B10HMGB1CXCL12ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0920413-B1 BORONIC COMPOUND COMPLEXING REAGENTS AND COMPLEXES PROLINX INC (US) 2002-11-13 EP claimed
US-8765649-B2 Lubricating oil composition NIPPON OIL CORPORATION (JP) 2014-07-01 US disclosed
US-8071518-B2 Low ash engine oil composition NIPPON OIL CORPORATION (JP) 2011-12-06 US disclosed
US-20090325835-A1 LUBRICATING OIL COMPOSITION YAGISHITA KAZUHIRO 2009-12-31 US disclosed
US-7629302-B2 Lubricating oil additive and lubricating oil composition NIPPON OIL CORPORATION (JP) 2009-12-08 US disclosed
US-7563751-B2 Lubricating oil composition NIPPON OIL CORPORATION (JP) 2009-07-21 US disclosed
US-20090075852-A1 Low Ash Engine Oil Composition NIPPON OIL CORPORATION (JP) 2009-03-19 US disclosed
EP-1997871-A1 LOW-ASH ENGINE OIL COMPOSITION Nippon Oil Corporation (JP) 2008-12-03 EP disclosed
CN-100347277-C Lubricating oil additive and lubricating oil composition NIPPON OIL CORP (JP) 2007-11-07 CN disclosed
CN-100344740-C Lubricating oil composition NIPPON OIL CORP (JP) 2007-10-24 CN disclosed
US-20060063686-A1 Lubricating oil additive and lubricating oil composition NIPPON OIL CORPORATION (JP) 2006-03-23 US disclosed
CN-1714140-A Lubricating oil additive and lubricating oil composition NIPPON OIL CORP (JP) 2005-12-28 CN disclosed
US-20050272616-A1 Lubricating oil composition NIPPON OIL CORPORATION (JP) 2005-12-08 US disclosed
EP-1580257-A1 LUBRICATING OIL ADDITIVE AND LUBRICATING OIL COMPOSITION Nippon Oil Corporation (JP) 2005-09-28 EP disclosed
CN-1675342-A Lubricating oil composition NIPPON OIL CORP (JP) 2005-09-28 CN disclosed
EP-1561799-A1 LUBRICATING OIL COMPOSITION Nippon Oil Corporation (JP) 2005-08-10 EP disclosed