Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGB1 | P09429 | 2/20 | 0.41 |
| ▸ | CXCL12 | P48061 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | ATIC | P31939 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.35 |
| ▸ | LDHA | P00338 | 2/20 | 0.35 |
| ▸ | LDHB | P07195 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3965068 | 0.80 | HSD17B10 (0.41) | HMGB1CXCL12MEN1KMT2AHSD17B10 | |
| SCHEMBL2053985 | 0.78 | GABRA1 (0.41) | HMGB1CXCL12HSD17B10HPGDALDH1A1 | |
| SCHEMBL29225947 | 0.78 | GABRA1 (0.41) | HMGB1CXCL12HSD17B10HPGDALDH1A1 | |
| SCHEMBL11061927 | 0.78 | KDM4E (0.41) | MEN1KMT2AHSD17B10ALDH1A1KDM4E | |
| SCHEMBL8072029 | 0.77 | GABRA1 (0.46) | MEN1KMT2AHPGDALDH1A1KDM4E | |
| SCHEMBL16035544 | 0.77 | GABRA1 (0.43) | MEN1KMT2AHSD17B10HPGDALDH1A1 | |
| SCHEMBL3364581 | 0.75 | PTPN1 (0.49) | HMGB1CXCL12MEN1KMT2AHSD17B10 | |
| SCHEMBL4074396 | 0.75 | ALDH1A1 (0.42) | HMGB1CXCL12HSD17B10HPGDALDH1A1 | |
| SCHEMBL9960069 | 0.75 | ALDH1A1 (0.47) | HMGB1CXCL12MEN1KMT2AHSD17B10 | |
| SCHEMBL22160245 | 0.74 | GABRA1 (0.38) | HMGB1CXCL12HSD17B10HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9902986-B2 | Enterobactin conjugates and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-02-27 | — | — | US | disclosed |
| WO-2015057958-A2 | ENTEROBACTIN CONJUGATES AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-04-23 | — | — | WO | disclosed |
| US-20150105337-A1 | ENTEROBACTIN CONJUGATES AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150105337-A1 | ENTEROBACTIN CONJUGATES AND USES THEREOF | BTD, VIP, SLC10A2 | HMGB1 51/4885CXCL12 1458/4885MEN1 1430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.