Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.50 |
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 4/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 4/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3963826 | 1.00 | KCNH2 (0.50) | KCNH2DRD2CHRM1SLC6A4SLC6A2 | |
| Oxalic Acid SCHEMBL3962175 | 0.97 | KCNH2 (0.48) | KCNH2DRD2CHRM1SLC6A4SLC6A2 | |
| Oxalic Acid SCHEMBL3962181 | 0.97 | KCNH2 (0.48) | KCNH2DRD2CHRM1SLC6A4SLC6A2 | |
| SCHEMBL3965943 | 0.88 | DRD2 (0.51) | KCNH2DRD2CHRM1SLC6A4SLC6A2 | |
| SCHEMBL3962107 | 0.88 | DRD2 (0.51) | KCNH2DRD2CHRM1SLC6A4SLC6A2 | |
| SCHEMBL3956191 | 0.87 | DRD2 (0.51) | KCNH2DRD2CHRM1SLC6A4SLC6A2 | |
| SCHEMBL3956189 | 0.87 | DRD2 (0.51) | KCNH2DRD2CHRM1SLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL3963423 | 0.87 | DRD2 (0.51) | KCNH2DRD2CHRM1SLC6A4SLC6A2 | |
| Oxalic Acid SCHEMBL3963899 | 0.85 | DRD2 (0.49) | KCNH2DRD2CHRM1SLC6A4SLC6A2 | |
| Oxalic Acid SCHEMBL3963911 | 0.85 | DRD2 (0.49) | KCNH2DRD2CHRM1SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101243075-A | Novel 2,3-dihydroindole compounds | LUNDBECK & CO AS H (DK) | 2008-08-13 | — | — | CN | claimed |
| EP-1928860-A1 | NOVEL 2,3-DIHYDROINDOLE COMPOUNDS | H.Lundbeck A/S (DK) | 2008-06-11 | — | — | EP | claimed |
| WO-2007019867-A1 | NOVEL 2,3-DIHYDROINDOLE COMPOUNDS | H. LUNDBECK A/S (DK) | 2007-02-22 | — | — | WO | claimed |
| US-20070043058-A1 | Novel 2,3-dihydroindole compounds | H. LUNDBECK A/S (DK) | 2007-02-22 | — | — | US | claimed |
| US-7544685-B2 | 2,3-dihydroindole compounds | H. LUNDBECK A/S (DK) | 2009-06-09 | — | — | US | disclosed |
| CN-101243075-A | Novel 2,3-dihydroindole compounds | LUNDBECK & CO AS H (DK) | 2008-08-13 | — | — | CN | disclosed |
| EP-1928860-A1 | NOVEL 2,3-DIHYDROINDOLE COMPOUNDS | H.Lundbeck A/S (DK) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007019867-A1 | NOVEL 2,3-DIHYDROINDOLE COMPOUNDS | H. LUNDBECK A/S (DK) | 2007-02-22 | — | — | WO | disclosed |
| US-20070043058-A1 | Novel 2,3-dihydroindole compounds | H. LUNDBECK A/S (DK) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043058-A1 | Novel 2,3-dihydroindole compounds | HTR2C, HTR2A, HTR5A | KCNH2 1354/4885DRD2 24/4885CHRM1 317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.