Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | ALPG | P10696 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.58 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.58 |
| ▸ | RHOA | P61586 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.51 |
| ▸ | RELA | Q04206 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | DHFR | P00374 | 2/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29833517 | 1.00 | NCF1 (0.61) | NCF1RAB9AKMT2AKDM4EMAPT | |
| SCHEMBL30760998 | 0.87 | NCF1 (0.71) | NCF1RAB9AKMT2AKDM4ERHOA | |
| SCHEMBL10458402 | 0.87 | NCF1 (0.71) | NCF1RAB9AKMT2AKDM4ERHOA | |
| SCHEMBL1703350 | 0.86 | NCF1 (0.55) | NCF1RAB9AKMT2AKDM4EMAPT | |
| SCHEMBL8564697 | 0.85 | NCF1 (0.53) | NCF1RAB9AKMT2AKDM4EMAPT | |
| SCHEMBL29110577 | 0.85 | NPC1 (0.58) | NCF1RAB9AKMT2AKDM4EMAPT | |
| SCHEMBL4494871 | 0.85 | KMT2A (0.58) | NCF1RAB9AKMT2AKDM4EMAPT | |
| SCHEMBL12431347 | 0.85 | NCF1 (0.58) | NCF1RAB9AKMT2AKDM4EMAPT | |
| SCHEMBL4812645 | 0.85 | NCF1 (0.53) | NCF1RAB9AKMT2AKDM4EMAPT | |
| SCHEMBL1702296 | 0.84 | SCN9A (0.52) | NCF1RAB9AKMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120136781-A | ROR 1-targeted inhibitor and synthesis method and application thereof | 北京大学 | 2025-06-13 | — | — | CN | claimed |
| CN-114907261-B | 2-phenylaminoquinoline derivative, preparation method and application thereof | 湖南中医药大学 | 2023-10-27 | — | — | CN | claimed |
| CN-114907261-A | 2-phenylamino quinoline derivative and preparation method and application thereof | 湖南中医药大学 | 2022-08-16 | — | — | CN | claimed |
| US-20190117683-A1 | ALGINATE OLIGOMERS FOR THE TREATMENT OR PREVENTION OF MICROBIAL OVERGROWTH IN THE INTESTINAL TRACT | ALGIPHARMA AS (NO) | 2019-04-25 | — | — | US | claimed |
| US-20180055873-A1 | USE OF ALGINATE OLIGOMERS AND CFTR MODULATORS IN THE TREATMENT OF CONDITIONS ASSOCIATED WITH CFTR DYSFUNCTION | ALGIPHARMA AS (NO) | 2018-03-01 | — | — | US | claimed |
| CN-107721923-A | 4 N anilino quinolines class compound synthesis and the application for preparing anti-Alzheimer disease medicine | 天津理工大学 | 2018-02-23 | — | — | CN | claimed |
| EP-3273995-A1 | USE OF ALGINATE OLIGOMERS AND CFTR MODULATORS IN THE TREATMENT OF CONDITIONS ASSOCIATED WITH CFTR DYSFUNCTION | ALGIPHARMA AS (NO) | 2018-01-31 | — | — | EP | claimed |
| WO-2017060388-A1 | ALGINATE OLIGOMERS FOR THE TREATMENT OR PREVENTION OF MICROBIAL OVERGROWTH IN THE INTESTINAL TRACT | ALGIPHARMA AS (NO) | 2017-04-13 | — | — | WO | claimed |
| WO-2016151051-A1 | USE OF ALGINATE OLIGOMERS AND CFTR MODULATORS IN THE TREATMENT OF CONDITIONS ASSOCIATED WITH CFTR DYSFUNCTION | ALGIPHARMA AS (NO) | 2016-09-29 | — | — | WO | claimed |
| CN-101180273-A | Methods of synthesizing 6-alkylaminoquinoline derivatives | WYETH CORP (US) | 2008-05-14 | — | — | CN | claimed |
| WO-2006127203-A2 | METHODS OF SYNTHESIZING 6-ALKYLAMINOQUINOLINE DERIVATIVES | WYETH (US) | 2006-11-30 | — | — | WO | claimed |
| US-20060270670-A1 | Methods of synthesizing 6-alkylaminoquinoline derivatives | WYETH | 2006-11-30 | — | — | US | claimed |
| US-5856337-A | 2-arylquinolines and process for producing the same | ASAHI GLASS CO., LTD. (JP) | 1999-01-05 | — | — | US | claimed |
| EP-0786460-A2 | 2-Arylquinolines and process for producing the same | ASAHI GLASS COMPANY LTD. (JP) | 1997-07-30 | — | — | EP | claimed |
| EP-0291809-B1 | 2-ANILINO-QUINOLINES, PROCESSES FOR THEIR PREPARATION AND FUNGICIDES CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1992-01-15 | — | — | EP | claimed |
| EP-0291809-A1 | 2-Anilino-quinolines, processes for their preparation and fungicides containing them | BASF Aktiengesellschaft (DE) | 1988-11-23 | — | — | EP | claimed |
| EP-0073875-B1 | AZO DYESTUFFS, PROCESS FOR THEIR PREPARATION AND THEIR USE | CASSELLA Aktiengesellschaft (DE) | 1988-09-07 | — | — | EP | claimed |
| US-4420308-A | Process for the production of reserve effects on polyester textiles and polyester/cellulose mixed fibre textiles: discharge printing with disperse azo dye with alkyl or alkoxy carbonyl, cyand and hydroxy phenyl group | CASSELLA AKTIENGESELLSCHAFT (DE) | 1983-12-13 | — | — | US | claimed |
| EP-0073875-A2 | Azo dyestuffs, process for their preparation and their use | CASSELLA Aktiengesellschaft (DE) | 1983-03-16 | — | — | EP | claimed |
| EP-0073876-A1 | Process for the production of reserve prints on polyester or polyester cellulose blended textiles | CASSELLA Aktiengesellschaft (DE) | 1983-03-16 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060270670-A1 | Methods of synthesizing 6-alkylaminoquinoline derivatives | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, RECQL, NQO2 | NCF1 2378/4885RAB9A 1046/4885KMT2A 794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.