Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B10 | O60218 | 6/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 6/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL397025 | 0.83 | ATM (0.39) | HCAR2APPMAPT | |
| SCHEMBL5701676 | 0.77 | ATM (0.34) | ALDH1A1HCAR2 | |
| SCHEMBL5701435 | 0.77 | ATM (0.39) | HCAR2APPMAPT | |
| SCHEMBL15404814 | 0.76 | AKR1B10 (0.40) | AKR1B10AKR1B1ALOX5ALDH1A1KDM4E | |
| SCHEMBL393259 | 0.75 | HCAR2 (0.37) | AKR1B10AKR1B1ALOX5ALDH1A1KDM4E | |
| SCHEMBL3309534 | 0.75 | AKR1B10 (0.39) | AKR1B10AKR1B1ALOX5ALDH1A1KDM4E | |
| SCHEMBL4623580 | 0.74 | HCAR2 (0.40) | AKR1B10AKR1B1ALOX5ALDH1A1KDM4E | |
| SCHEMBL22092326 | 0.74 | HCAR2 (0.40) | AKR1B10AKR1B1ALOX5ALDH1A1KDM4E | |
| SCHEMBL396538 | 0.73 | — | — | |
| SCHEMBL7794491 | 0.73 | HCAR2 (0.39) | AKR1B10AKR1B1ALOX5ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110697-B2 | Method for the production of polymerizable silicones | WACKER CHEMIE AG (DE) | 2012-02-07 | — | — | US | disclosed |
| US-8101789-B2 | Method for the production of polymerizable silicones | WACKER CHEMIE AG (DE) | 2012-01-24 | — | — | US | disclosed |
| EP-2125833-B1 | METHOD FOR THE PRODUCTION OF POLYMERISABLE SILICONES | WACKER CHEMIE AG (DE) | 2010-08-25 | — | — | EP | disclosed |
| EP-2125834-B1 | METHOD FOR THE PRODUCTION OF POLYMERISABLE SILICONES | WACKER CHEMIE AG (DE) | 2010-08-25 | — | — | EP | disclosed |
| US-20100041909-A1 | METHOD FOR THE PRODUCTION OF POLYMERIZABLE SILICONES | WACKER CHEMIE AG (DE) | 2010-02-18 | — | — | US | disclosed |
| US-20100029972-A1 | METHOD FOR THE PRODUCTION OF POLYMERIZABLE SILICONES | WACKER CHEMIE AG (DE) | 2010-02-04 | — | — | US | disclosed |