Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 6/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4065260 | 0.84 | KDM4E (0.37) | KDM4EGAAGLAHSD17B10GRIN2D | |
| SCHEMBL13907960 | 0.74 | TPMT (0.42) | KDM4EGAAHSD17B10GRIN2DGRIN3B | |
| SCHEMBL2489749 | 0.73 | KDM4E (0.40) | KDM4EGAAGLAHSD17B10MAPT | |
| SCHEMBL8603982 | 0.72 | KMT2A (0.41) | KDM4EGAAGLAHSD17B10MAPT | |
| SCHEMBL3962137 | 0.71 | DHODH (0.43) | ALDH1A1HPGDPOLBRAB9A | |
| SCHEMBL2257694 | 0.70 | GRIN2D (0.69) | KDM4EGAAHSD17B10GRIN2DGRIN3B | |
| SCHEMBL13907978 | 0.70 | BCL6 (0.45) | KDM4EGAAHSD17B10MAPTALDH1A1 | |
| SCHEMBL17758386 | 0.67 | GRIN2D (0.44) | KDM4EGAAGLAHSD17B10GRIN2D | |
| SCHEMBL19779947 | 0.67 | GRIN1 (0.48) | KDM4EHSD17B10GRIN2DGRIN3BGRIN1 | |
| SCHEMBL9413571 | 0.67 | PRKCZ (0.40) | KDM4EGAAGLAHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034029-A2 | 1-SUBSTITUTED 4-HETEROCYCLYLPIPERIDINES FOR USE AS CGRP ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-03-19 | — | — | WO | disclosed |