SCHEMBL3966178

SCHEMBL3966178

O=C(O)CC(=O)CC/C=C/CCC(=O)CC(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 4/20 0.43
ALDH1A1 P00352 3/20 0.43
MAPT P10636 3/20 0.43
CYP19A1 P11511 2/20 0.43
FFAR1 O14842 1/20 0.43
RXRA P19793 1/20 0.43
OXER1 Q8TDS5 1/20 0.43
LDHA P00338 1/20 0.42
SRR Q9GZT4 1/20 0.42
KDM4E B2RXH2 1/20 0.39
KDM6B O15054 1/20 0.39
KDM5C P41229 1/20 0.39
EGLN1 Q9GZT9 1/20 0.39
PHF8 Q9UPP1 1/20 0.39
KDM2A Q9Y2K7 1/20 0.39
FAAH O00519 2/20 0.38
EPHX2 P34913 1/20 0.37
TERT O14746 3/20 0.37
PTPN1 P18031 3/20 0.37
PPARD Q03181 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3966182 1.00 PPARG (0.43) PPARGALDH1A1MAPTCYP19A1FFAR1
SCHEMBL9067968 0.87 KDM4E (0.39) PPARGALDH1A1MAPTCYP19A1FFAR1
SCHEMBL5229289 0.87 MMP12 (0.37) PPARGALDH1A1MAPTCYP19A1FFAR1
SCHEMBL9067970 0.87 KDM4E (0.39) PPARGALDH1A1MAPTCYP19A1FFAR1
SCHEMBL16681683 0.85 LDHA (0.35) PPARGALDH1A1MAPTCYP19A1FFAR1
SCHEMBL9638651 0.85 FNTA (0.35) PPARGALDH1A1MAPTCYP19A1FFAR1
SCHEMBL10437539 0.82 MAPT (0.33) PPARGALDH1A1MAPTCYP19A1FFAR1
SCHEMBL10437538 0.82 MAPT (0.33) PPARGALDH1A1MAPTCYP19A1FFAR1
SCHEMBL11709587 0.82 PPARG (0.67) PPARGALDH1A1MAPTCYP19A1FFAR1
SCHEMBL18342627 0.81 EGLN1 (0.42) MAPTLDHASRRKDM4EKDM6B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2941460-B1 ONE -COMPONENT, CURABLE COATING COMPOSITION, PROCESSES FOR MAKING AND USING THEM, AND COATINGS AND ARTICLES PREPARED WITH THEM BASF COATINGS GMBH (DE) 2017-11-22 EP disclosed
US-9683125-B2 One-component, curable coating compositions, processes for making and using them, and coatings and articles prepared with them BASF COATINGS GMBH (DE) 2017-06-20 US disclosed
US-20150337159-A1 One-Component, Curable Coating Compositions, Processes For Making And Using Them, And Coatings And Articles Prepared With Them BASF COATINGS GMBH (DE) 2015-11-26 US disclosed
EP-2941460-A1 ONE -COMPONENT, CURABLE COATING COMPOSITION, PROCESSES FOR MAKING AND USING THEM, AND COATINGS AND ARTICLES PREPARED WITH THEM BASF Coatings GmbH (DE) 2015-11-11 EP disclosed
WO-2014106552-A1 ONE -COMPONENT, CURABLE COATING COMPOSITION, PROCESSES FOR MAKING AND USING THEM, AND COATINGS AND ARTICLES PREPARED WITH THEM BASF COATINGS GMBH (DE) 2014-07-10 WO disclosed
EP-1088040-B1 Use of a crosslinking component comprising a polyamine, a polyketimine or combination thereof DU PONT (US) 2009-07-29 EP disclosed
EP-1358286-B1 AMBIENT CURE FAST DRY SOLVENT BORNE COATING COMPOSITIONS DU PONT (US) 2006-01-04 EP disclosed
US-6740359-B2 SOLVENT RESISTANCE; WATERPROOFING; PROTECTIVE COATINGS E. I. DU PONT DE NEMOURS AND COMPANY 2004-05-25 US disclosed
EP-1358286-A1 AMBIENT CURE FAST DRY SOLVENT BORNE COATING COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-11-05 EP disclosed
EP-1177265-B1 COATING COMPOSITIONS CONTAINING HIGHLY STRUCTURED MACROMOLECULES DU PONT (US) 2003-09-17 EP disclosed
US-6432484-B1 CURABLE LIQUID COATINGS E. I. DU PONT DE NEMOURS AND COMPANY 2002-08-13 US disclosed
US-6432483-B1 CURABLE LIQUID COATINGS E. I. DU PONT DE NEMOURS & COMPANY 2002-08-13 US disclosed
EP-1177265-A1 COATING COMPOSITIONS CONTAINING HIGHLY STRUCTURED MACROMOLECULES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2002-02-06 EP disclosed
WO-2000068331-A1 COATING COMPOSITIONS CONTAINING HIGHLY STRUCTURED MACROMOLECULES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2000-11-16 WO disclosed
EP-0199087-B2 A liquid coating composition and a process for coating a substrate with such coating composition AKZO NV (NL) 1993-11-10 EP disclosed
US-4929661-A Aqueous coating composition containing a functional organic compound, a curing agent, and a dispersing agent AKZO N.V. (NL) 1990-05-29 US disclosed
EP-0199087-B1 A LIQUID COATING COMPOSITION AND A PROCESS FOR COATING A SUBSTRATE WITH SUCH COATING COMPOSITION AKZO N.V. (NL) 1989-01-18 EP disclosed
US-4772680-A Liquid coating composition and a process for coating a substrate with such coating composition AKZO N.V. (NL) 1988-09-20 US disclosed
EP-0264983-A1 An aqueous coating composition and a process of coating a substrate with such coating composition AKZO N.V. (NL) 1988-04-27 EP disclosed
EP-0199087-A1 A liquid coating composition and a process for coating a substrate with such coating composition AKZO N.V. (NL) 1986-10-29 EP disclosed