Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.71 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.71 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.69 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | PTGES | O14684 | 1/20 | 0.66 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.66 |
| ▸ | KDR | P35968 | 1/20 | 0.61 |
| ▸ | IDH1 | O75874 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | IDH2 | P48735 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1462338 | 0.90 | NTRK1 (0.73) | NTRK1CDK19GRIK1GRIK2MEN1 | |
| SCHEMBL8432788 | 0.86 | PTGES (0.74) | NTRK1CDK19GRIK1GRIK2MEN1 | |
| SCHEMBL6431220 | 0.85 | KDR (0.67) | NTRK1CDK19GRIK1MEN1KMT2A | |
| SCHEMBL5597796 | 0.84 | NTRK1 (0.79) | NTRK1CDK19GRIK1MEN1KMT2A | |
| SCHEMBL14459434 | 0.84 | KMT2A (0.74) | NTRK1CDK19GRIK1MEN1KMT2A | |
| SCHEMBL4218069 | 0.83 | KDR (0.61) | NTRK1CDK19GRIK1MEN1KMT2A | |
| SCHEMBL29763181 | 0.83 | NTRK1 (1.00) | NTRK1CDK19GRIK1MEN1KMT2A | |
| SCHEMBL1463468 | 0.83 | NTRK1 (1.00) | NTRK1CDK19GRIK1MEN1KMT2A | |
| SCHEMBL4175803 | 0.82 | GRIK1 (1.00) | GRIK1GRIK2MEN1KMT2AIDH1 | |
| SCHEMBL1463283 | 0.82 | NTRK1 (0.76) | NTRK1CDK19GRIK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521480-B2 | Aryl ureido benzoic acid derivatives and their use | NEUROSEARCH (DK) | 2009-04-21 | — | — | US | claimed |
| US-20060069255-A1 | Novel aryl ureido benzoic acid derivatives and their use | NEUROSEARCH (DK) | 2006-03-30 | — | — | US | claimed |
| EP-1565429-A2 | ARYL UREIDO DERIVATIVES AND THEIR MEDICAL USE | NEUROSEARCH A/S (DK) | 2005-08-24 | — | — | EP | claimed |
| WO-2004046090-A2 | ARYL UREIDO DERIVATIVES AND THEIR MEDICAL USE | NEUROSEARCH A/S (DK) | 2004-06-03 | — | — | WO | claimed |
| US-7521480-B2 | Aryl ureido benzoic acid derivatives and their use | NEUROSEARCH (DK) | 2009-04-21 | — | — | US | disclosed |
| US-20060069255-A1 | Novel aryl ureido benzoic acid derivatives and their use | NEUROSEARCH (DK) | 2006-03-30 | — | — | US | disclosed |
| EP-1565429-A2 | ARYL UREIDO DERIVATIVES AND THEIR MEDICAL USE | NEUROSEARCH A/S (DK) | 2005-08-24 | — | — | EP | disclosed |
| WO-2004046090-A2 | ARYL UREIDO DERIVATIVES AND THEIR MEDICAL USE | NEUROSEARCH A/S (DK) | 2004-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060069255-A1 | Novel aryl ureido benzoic acid derivatives and their use | GABRA5, GRIK5, GRM5 | NTRK1 727/4885CDK19 3729/4885GRIK1 24/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.