Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4405552 | 0.76 | MCHR1 (0.45) | PARP10MCHR1 | |
| SCHEMBL4429009 | 0.72 | MCHR1 (0.52) | PARP10PARP15MCHR1 | |
| SCHEMBL5781772 | 0.71 | RIPK1 (0.54) | PARP10PARP15MCHR1 | |
| SCHEMBL30580721 | 0.70 | TLR4 (0.46) | PARP10PARP15 | |
| SCHEMBL2202527 | 0.70 | TLR4 (0.46) | PARP10PARP15 | |
| SCHEMBL1002808 | 0.70 | TLR4 (0.46) | PARP10PARP15 | |
| SCHEMBL2204247 | 0.70 | TLR4 (0.46) | PARP10PARP15 | |
| SCHEMBL2207625 | 0.69 | PARP10 (0.42) | PARP10PARP15THRATHRB | |
| SCHEMBL2207362 | 0.69 | SLC2A1 (0.44) | PARP10PARP15 | |
| SCHEMBL2206503 | 0.67 | TLR4 (0.45) | PARP10PARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091955-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | Acucela, Inc. (US) | 2009-08-26 | — | — | EP | disclosed |
| WO-2009045479-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. (US) | 2009-04-09 | — | — | WO | disclosed |