Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL20187811 | 0.83 | RIPK1 (0.46) | MCHR1HTR2C | |
| SCHEMBL18466652 | 0.80 | MCHR1 (0.50) | MCHR1PARP10 | |
| SCHEMBL13537842 | 0.77 | MCHR1 (0.55) | MCHR1HTR2CPARP10 | |
| SCHEMBL3966732 | 0.76 | PARP10 (0.38) | MCHR1PARP10 | |
| SCHEMBL16501544 | 0.75 | SLC6A4 (0.47) | MCHR1HTR2CPARP10 | |
| SCHEMBL18706829 | 0.75 | MCHR1 (0.48) | MCHR1HTR2C | |
| SCHEMBL20083011 | 0.75 | MCHR1 (0.48) | MCHR1 | |
| SCHEMBL20190412 | 0.74 | DUT (0.38) | — | |
| SCHEMBL29786709 | 0.74 | RIPK1 (0.54) | MCHR1HTR2CPARP10 | |
| SCHEMBL20472353 | 0.74 | RIPK1 (0.54) | MCHR1HTR2CPARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091955-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | Acucela, Inc. (US) | 2009-08-26 | — | — | EP | disclosed |
| WO-2009045479-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. (US) | 2009-04-09 | — | — | WO | disclosed |