Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.52 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2544954 | 0.82 | GABRA1 (0.40) | GABRA1GABRB2FAAHGABRG2GABRB3 | |
| SCHEMBL66162 | 0.81 | GABRA1 (0.63) | GABRA1GABRB2FAAHGABRG2GABRB3 | |
| SCHEMBL29429205 | 0.81 | GABRA1 (0.63) | GABRA1GABRB2FAAHGABRG2GABRB3 | |
| SCHEMBL199413 | 0.79 | GABRA1 (0.57) | GABRA1GABRB2FAAHGABRG2GABRB3 | |
| SCHEMBL14830645 | 0.78 | FFAR1 (0.42) | GABRA1GABRB2FAAHGABRG2GABRB3 | |
| SCHEMBL19640328 | 0.78 | GABRA1 (0.37) | GABRA1GABRB2FAAHGABRG2GABRB3 | |
| SCHEMBL6829698 | 0.78 | GABRA1 (0.37) | GABRA1GABRB2FAAHGABRG2GABRB3 | |
| SCHEMBL3417544 | 0.78 | GABRA1 (0.37) | GABRA1GABRB2FAAHGABRG2GABRB3 | |
| SCHEMBL810349 | 0.78 | GABRA1 (0.42) | GABRA1GABRB2FAAHGABRG2GABRB3 | |
| SCHEMBL98101 | 0.78 | CYP2D6 (0.46) | GABRA1GABRB2LMNACYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1368 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117831652-A | Prediction method of olefin hydroformylation positive-to-negative ratio | 上海华谊控股集团有限公司 | 2024-04-05 | — | — | CN | claimed |
| CN-114736096-B | Benzocyclobutene monomer, benzocyclobutene resin, preparation thereof, low dielectric material and application thereof | 华为技术有限公司 | 2023-07-28 | — | — | CN | claimed |
| CN-116410239-A | Heteroatom-containing metallocene compound and preparation method and application thereof | 惠生(中国)投资有限公司 | 2023-07-11 | — | — | CN | claimed |
| CN-110818545-B | Method for preparing substituted aryl ketone by ketone arylation | 上海化工研究院有限公司 | 2022-12-09 | — | — | CN | claimed |
| CN-110922286-B | Asymmetric aryl substituted fulvene compound and preparation method and application thereof | 上海化工研究院有限公司 | 2022-08-16 | — | — | CN | claimed |
| CN-110922286-A | Asymmetric aryl substituted fulvene compound and preparation method and application thereof | 上海化工研究院有限公司 | 2020-03-27 | — | — | CN | claimed |
| CN-110818545-A | Method for preparing substituted aryl ketone by ketone arylation | 上海化工研究院有限公司 | 2020-02-21 | — | — | CN | claimed |
| EP-1465869-B1 | MODULATORS OF LXR | EXELIXIS PATENT CO LLC (US) | 2013-05-15 | — | — | EP | claimed |
| US-7998986-B2 | Heterocyclic compounds, in particular N-substituted pyridones for modulating the activity of nuclear receptors | EXELIXIS PATENT COMPANY LLC (US) | 2011-08-16 | — | — | US | claimed |
| EP-2328856-A2 | SPECIFIC BRANCHED ALDEHYDES, ALCOHOLS, SURFACTANTS AND CONSUMER PRODUCTS BASED THEREON | The Procter & Gamble Company (US) | 2011-06-08 | — | — | EP | claimed |
| JP-2005536450-A | — | — | 2005-12-02 | — | — | JP | claimed |
| CN-1177258-C | Photo-thermo-sensitive imaging material | ��ʿ��Ƭ��ʽ���� | 2004-11-24 | — | — | CN | claimed |
| EP-1465869-A1 | MODULATORS OF LXR | X-Ceptor Therapeutics, Inc. (US) | 2004-10-13 | — | — | EP | claimed |
| US-6677382-B1 | HALOGENATED OXYAMINES, USED AS ENZYME INHIBITORS FOR PROPHYLAXIS OF ATHEROSCLEROSIS AND CARDIOVASCULAR DISORDERS, AND AS ANTILIPEMIC AGENTS | PHARMACIA CORPORATION | 2004-01-13 | — | — | US | claimed |
| US-20030191306-A1 | Substituted N-Aliphatic-N-Aromatictertiary-Heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | G.D. SEARLE & CO. (US) | 2003-10-09 | — | — | US | claimed |
| US-20030181420-A1 | Heterocyclic compounds, in particular N-substituted pyridones for modulating the activity of nuclear receptors | EXELIXIS, INC. | 2003-09-25 | — | — | US | claimed |
| WO-2003059884-A1 | MODULATORS OF LXR | X-CEPTOR THERAPEUTICS, INC. (US) | 2003-07-24 | — | — | WO | claimed |
| WO-2000072395-A2 | SULFONATED POLYPHOSPHAZENES FOR PROTON-EXCHANGE MEMBRANE FUEL CELLS | ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2000-11-30 | — | — | WO | claimed |
| EP-0573182-B1 | Process for extracting metal values | AVECIA LTD (GB) | 2000-01-05 | — | — | EP | claimed |
| US-4113495-A | 2,4,4-TRIMETHYL-2-(2,5-DIHYDROXYPHENYL)-6-HYDROXY-CHROMANS | FUJI PHOTO FILM CO., LTD. (JP) | 1978-09-12 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030191306-A1 | Substituted N-Aliphatic-N-Aromatictertiary-Heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | CETP, DBI, MTTP | GABRA1 4462/4885GABRB2 4337/4885FAAH 741/4885 |
| US-20030181420-A1 | Heterocyclic compounds, in particular N-substituted pyridones for modulating the activity of nuclear receptors | NR1H2, NR1H3, NCOA1 | GABRA1 534/4885GABRB2 749/4885FAAH 1611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.