SCHEMBL6829698

SCHEMBL6829698

CC(Cl)c1ccccc1[O]

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.37
GABRB2 P47870 2/20 0.37
ADRB2 P07550 1/20 0.34
ADRB1 P08588 1/20 0.34
LMNA P02545 5/20 0.33
TSHR P16473 3/20 0.33
FAAH O00519 2/20 0.33
HPGD P15428 2/20 0.33
CYP1A2 P05177 2/20 0.33
CYP3A4 P08684 2/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
GABRB1 P18505 1/20 0.33
GABRG2 P18507 1/20 0.33
PTGS1 P23219 1/20 0.33
SLC6A2 P23975 1/20 0.33
HTR2C P28335 1/20 0.33
GABRB3 P28472 1/20 0.33
GABRA5 P31644 1/20 0.33
GABRA3 P34903 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2865478 0.83 GABRA1 (0.43) GABRA1GABRB2ADRB2ADRB1LMNA
SCHEMBL396706 0.78 GABRA1 (0.52) GABRA1GABRB2LMNATSHRFAAH
SCHEMBL2544954 0.78 GABRA1 (0.40) GABRA1GABRB2ADRB2ADRB1LMNA
SCHEMBL11443844 0.76 GABRA1 (0.40) GABRA1GABRB2ADRB2ADRB1LMNA
SCHEMBL11501742 0.76 GABRA1 (0.50) GABRA1GABRB2LMNATSHRFAAH
SCHEMBL587834 0.75 GABRA1 (0.34) GABRA1GABRB2LMNATSHRFAAH
SCHEMBL98101 0.74 CYP2D6 (0.46) GABRA1GABRB2LMNATSHRCYP1A2
SCHEMBL19640328 0.74 GABRA1 (0.37) GABRA1GABRB2ADRB2ADRB1LMNA
SCHEMBL14830645 0.74 FFAR1 (0.42) GABRA1GABRB2ADRB2ADRB1LMNA
SCHEMBL810349 0.74 GABRA1 (0.42) GABRA1GABRB2ADRB2ADRB1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6746757-B1 Multilayered molding MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2004-06-08 US disclosed
EP-0852604-B1 A POLYPHENYLENE OXIDE DELIVERY SYSTEM FOR ADHESIVE COMPOSITIONS ARIZONA CHEM (US) 2002-04-10 EP disclosed
US-5910526-A HEATING AND MIXING PREBLEND COMPRISING A POLYPHENYLENE ETHER AND B-BLOCK COMPATIBLE RESIN TOGETHER WITH STYRENIC-CONJUGATED DIENE-STRYRENIC-A-B-A BLOCK POLYMER; HIGHER TEMPERAURE HOT MELT ADHESIVES ARIZONA CHEMICAL COMPANY (US) 1999-06-08 US disclosed
US-5807915-A HEAT RESISTANCE ARIZONA CHEMICAL COMPANY (US) 1998-09-15 US disclosed
EP-0852604-A4 1998-08-26 EP disclosed
US-5789474-A HOT MELT ADHESIVE ARIZONA CHEMICAL COMPANY (US) 1998-08-04 US disclosed
EP-0852604-A1 A POLYPHENYLENE OXIDE DELIVERY SYSTEM FOR ADHESIVE COMPOSITIONS ARIZONA CHEMICAL COMPANY (US) 1998-07-15 EP disclosed
EP-0381056-B1 Method for preparing an impact resistant thermoplastic resin composition MITSUBISHI CHEM CORP (JP) 1997-09-03 EP disclosed
WO-1997011997-A1 A POLYPHENYLENE OXIDE DELIVERY SYSTEM FOR ADHESIVE COMPOSITIONS ARIZONA CHEMICAL COMPANY (US) 1997-04-03 WO disclosed
EP-0520146-B1 Process for preparing a thermoplastic resin composition MITSUBISHI CHEM CORP (JP) 1997-01-15 EP disclosed
EP-0454156-A2 Thermoplastic resin composition MITSUBISHI CHEMICAL CORPORATION (JP) 1991-10-30 EP disclosed
US-5026787-A Blends of polyphenylene ether, polyamides, unsaturated compounds MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1991-06-25 US disclosed
US-5001181-A polyamide blends with dispersed particles of polyphenylene ether which contain dispersed filler particles; strength, flexibility, solvent resistance MITSUBISHI PETROCHEMICAL COMPANY, LTD. (JP) 1991-03-19 US disclosed
EP-0415344-A1 Resin composition and process for preparing it MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1991-03-06 EP disclosed
EP-0381056-A2 Impact resistant thermoplastic resin composition MITSUBISHI CHEMICAL CORPORATION (JP) 1990-08-08 EP disclosed
EP-0357065-A2 Resin composition MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1990-03-07 EP disclosed
EP-0067217-A4 COMPOSITIONS OF POLYPHENYLENE OXIDES WITH EPDM-SILICONE RUBBER. GEN ELECTRIC (US) 1983-05-16 EP disclosed
EP-0067217-A1 COMPOSITIONS OF POLYPHENYLENE OXIDES WITH EPDM-SILICONE RUBBER GENERAL ELECTRIC COMPANY (US) 1982-12-22 EP disclosed
US-4365042-A Compositions of polyphenylene oxides with EPDM-silicone rubber GENERAL ELECTRIC COMPANY (US) 1982-12-21 US disclosed
WO-1982002204-A1 COMPOSITIONS OF POLYPHENYLENE OXIDES WITH EPDM-SILICONE RUBBER GEN ELECTRIC (US) 1982-07-08 WO disclosed