Hydrochloric Acid

Hydrochloric Acid

SCHEMBL3967100

CCCCCCCCO[Ti+3].[Cl-].[Cl-].[Cl-]

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.47
THRB P10828 2/20 0.47
MEN1 O00255 1/20 0.42
HTT P42858 1/20 0.42
KMT2A Q03164 1/20 0.42
MAPT P10636 1/20 0.42
LPAR3 Q9UBY5 6/20 0.41
CA1 P00915 6/20 0.41
CA2 P00918 6/20 0.41
CA9 Q16790 6/20 0.41
LPAR2 Q9HBW0 5/20 0.41
LPAR1 Q92633 2/20 0.41
CA12 O43570 2/20 0.41
CA3 P07451 2/20 0.41
CA4 P22748 2/20 0.41
CA6 P23280 2/20 0.41
CA5A P35218 2/20 0.41
CA7 P43166 2/20 0.41
CA14 Q9ULX7 2/20 0.41
CA5B Q9Y2D0 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9238202 1.00 TSHR (0.47) TSHRTHRBMEN1HTTKMT2A
Hydrochloric Acid SCHEMBL11125894 0.97 TSHR (0.41) TSHRTHRBMEN1HTTKMT2A
SCHEMBL31590367 0.94 THRB (0.47) TSHRTHRBMEN1HTTKMT2A
Hydrochloric Acid SCHEMBL236053 0.88
SCHEMBL31659029 0.84
SCHEMBL3803753 0.73 TSHR (0.50) TSHRTHRBMEN1HTTKMT2A
Heptane SCHEMBL5048015 0.73
SCHEMBL21341773 0.71 THRB (0.70) TSHRTHRBMEN1HTTKMT2A
SCHEMBL21044639 0.71 THRB (0.70) TSHRTHRBMEN1HTTKMT2A
SCHEMBL22268781 0.71 THRB (0.70) TSHRTHRBMEN1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100577270-C Porous film, and production method and applications thereof SUMITOMO CHEMICAL CO 2010-01-06 CN disclosed
US-7566676-B2 Preparation method of solid titanium catalyst for olefin polymerization SAMSUNG TOTAL PETROCHEMICALS CO., LTD. (KR) 2009-07-28 US disclosed
US-20080167179-A1 Preparation Method of Solid Titanium Catalyst for Olefin Polymerization SAMSUNG TOTAL PETROCHEMICALS CO., INC. (KR) 2008-07-10 US disclosed
EP-1718682-A1 PREPARATION METHOD OF SOLID TITANIUM CATALYST FOR OLEFIN POLYMERIZATION Samsung Total Petrochemicals Co. Ltd. (KR) 2006-11-08 EP disclosed
CN-1846840-A Porous film, and production method and applications thereof SUMITOMO CHEMICAL CO (JP) 2006-10-18 CN disclosed
WO-2005082950-A1 PREPARATION METHOD OF SOLID TITANIUM CATALYST FOR OLEFIN POLYMERIZATION SAMSUNG TOTAL PETROCHEMICALS CO., LTD. (KR) 2005-09-09 WO disclosed
US-5122490-A Composed of organomagesium compounds, titanium and vanadium halides, alcohols, halogenated silanes, siloxanes, borates, electron donors and cyclic ether CHISSO CORPORATION (JP) 1992-06-16 US disclosed
EP-0174116-B1 POLYMERIZATION CATALYST EXXON RESEARCH AND ENGINEERING COMPANY (US) 1992-04-29 EP disclosed
EP-0175475-B1 POLYMERIZATION CATALYST EXXON RESEARCH AND ENGINEERING COMPANY (US) 1990-01-24 EP disclosed
US-4831091-A USING A COORDINATION CATALYST CONTAINING A SILANETRIOL OR -DIOL AS WELL AS AN AROMATIC ESTSER; ODORLESS; STEREOSPECIFIC; PARTICLE SIZES CHISSO CORPORATION (JP) 1989-05-16 US disclosed
US-4578373-A Polymerization catalyst system EXXON RESEARCH & ENGINEERING CO. (US) 1986-03-25 US disclosed
EP-0172021-A2 Polymerization catalyst EXXON RESEARCH AND ENGINEERING COMPANY (US) 1986-02-19 EP disclosed
EP-0170384-A2 Polymerization catalyst EXXON RESEARCH AND ENGINEERING COMPANY (US) 1986-02-05 EP disclosed
US-4568730-A IMPREGNATING CATALYST INTO POLYETHYLENE, HEATING IN LIQUID IN WHICH POLYETHYLENE IS INSOLUBLE EXXON RESEARCH & ENGINEERING CO. (US) 1986-02-04 US disclosed
US-4567153-A Polymerization catalyst comprising copulverized solid magnesium compound and solid halide of scandium EXXON RESEARCH & ENGINEERING CO. (US) 1986-01-28 US disclosed
US-4562170-A Polymerization catalyst EXXON RESEARCH & ENGINEERING CO. (US) 1985-12-31 US disclosed
US-4554265-A POLYOLEFINS HAVING BROAD MOLECULAR WEIGHT DISTRIBUTION EXXON RESEARCH & ENGINEERING CO. (US) 1985-11-19 US disclosed
US-4551439-A Solid catalyst component for olefin polymerization and process for producing same CHISSO CORPORATION (JP) 1985-11-05 US disclosed
US-4471066-A Polymerization of olefins ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1984-09-11 US disclosed
EP-0058549-A2 Catalyst for polymerization of olefins Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1982-08-25 EP disclosed