Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | LIG1 | P18858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1482988 | 0.82 | ALDH1A1 (0.68) | HPGDTSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL29690311 | 0.82 | ALDH1A1 (0.68) | HPGDTSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL3944635 | 0.81 | HPGD (0.49) | HPGDTSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL28190797 | 0.80 | HPGD (0.47) | HPGDTSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL5042380 | 0.80 | ERN1 (0.57) | HPGDTSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL2522004 | 0.80 | HPGD (0.47) | HPGDTSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL1579244 | 0.79 | ALDH1A1 (0.48) | HPGDMAPK1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL5460266 | 0.79 | HTR2C (0.46) | HPGDTSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL20690103 | 0.79 | HPGD (0.46) | HPGDTSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL28623220 | 0.78 | ALDH1A1 (0.56) | HPGDALDH1A1HTTSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363876-B1 | GLUCOCORTICOID RECEPTOR MODULATORS | KAROBIO AB (SE) | 2009-07-29 | — | — | EP | disclosed |