Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6324979 | 0.83 | THRB (0.35) | TDP1ALDH1A1 | |
| SCHEMBL19100150 | 0.83 | — | — | |
| SCHEMBL10716607 | 0.83 | ALDH1A1 (0.39) | LMNAALDH1A1 | |
| SCHEMBL13071710 | 0.80 | — | — | |
| SCHEMBL9979302 | 0.79 | ALDH1A1 (0.33) | TDP1ALDH1A1HPGDHIF1A | |
| SCHEMBL767030 | 0.77 | — | — | |
| SCHEMBL11499452 | 0.77 | — | — | |
| SCHEMBL28272450 | 0.77 | — | — | |
| SCHEMBL62388 | 0.76 | — | — | |
| Water SCHEMBL28322585 | 0.75 | TDP1 (0.35) | TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9125856-B1 | Method of stabilizing human eye tissue | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2015-09-08 | — | — | US | disclosed |
| WO-2014158445-A1 | SYNTHESIS OF (2-NITRO)ALKYL (METH)ACRYLATES VIA TRANSESTERIFICATION OF (METH)ACRYLATE ESTERS | ROHM AND HAAS COMPANY (US) | 2014-10-02 | — | — | WO | disclosed |
| EP-2082005-A1 | LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS | Pleotint, L.L.C. (US) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008028128-A1 | LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS | PLEOTINT, L.L.C. (US) | 2008-03-06 | — | — | WO | disclosed |