Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3138658 | 0.74 | ALDH1A1 (0.35) | ALDH1A1SOAT1LMNAHSD17B10TSHR | |
| SCHEMBL31448947 | 0.63 | — | — | |
| SCHEMBL13177331 | 0.61 | FFAR3 (0.40) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| SCHEMBL8530828 | 0.61 | FFAR3 (0.40) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| SCHEMBL19598979 | 0.59 | ALDH1A1 (0.81) | ALDH1A1SOAT1LMNAHSD17B10TSHR | |
| SCHEMBL1718009 | 0.59 | ALDH1A1 (0.81) | ALDH1A1SOAT1LMNAHSD17B10TSHR | |
| SCHEMBL14479589 | 0.59 | — | — | |
| SCHEMBL1958756 | 0.59 | ALDH1A1 (1.00) | ALDH1A1SOAT1LMNAHSD17B10TSHR | |
| SCHEMBL3673 | 0.59 | — | — | |
| SCHEMBL9802069 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054375-A2 | PROCESS OF PREPARING A GAMMA-AMINO ACID | Merck Generics (UK) Limited (GB) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008007145-A2 | PROCESS OF PREPARING A GAMMA-AMINO ACID | GENERICS [UK] LIMITED (GB) | 2008-01-17 | — | — | WO | disclosed |