Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.51 |
| ▸ | P4HB | P07237 | 4/20 | 0.48 |
| ▸ | KDR | P35968 | 3/20 | 0.44 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4461043 | 0.85 | SNCA (0.52) | P4HBKDRCXCL12MAOAMAOB | |
| SCHEMBL1404873 | 0.77 | IAPP (0.65) | APPP4HBCXCL12 | |
| SCHEMBL1404874 | 0.77 | IAPP (0.65) | APPP4HBCXCL12 | |
| SCHEMBL11971419 | 0.76 | APP (0.60) | APPP4HB | |
| SCHEMBL11971417 | 0.76 | APP (0.60) | APPP4HB | |
| SCHEMBL18551815 | 0.76 | MAOA (0.51) | P4HBKDRMAOAMAOB | |
| SCHEMBL11999778 | 0.75 | APP (0.56) | APPP4HBCXCL12 | |
| SCHEMBL21219011 | 0.74 | CYP1A2 (0.56) | KDR | |
| SCHEMBL499507 | 0.74 | CYP1A2 (0.56) | KDR | |
| SCHEMBL6781413 | 0.73 | KDR (0.52) | P4HBKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7566737-B2 | Combinations of substituted 1,3-diphenylprop-2-en-1-one derivatives with other therapeutically active ingredients | GENFIT (FR) | 2009-07-28 | — | — | US | disclosed |
| US-20070032543-A1 | Combinations of substituted 1,3-diphenylprop-2-EN-1-one derivatives with other therapeutically active ingredients | GENFIT (FR) | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032543-A1 | Combinations of substituted 1,3-diphenylprop-2-EN-1-one derivatives with other therapeutically active ingredients | PSEN1, BACE1, PSEN2 | APP 7/4885P4HB 4001/4885KDR 150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.