Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8617571 | 0.89 | HTT (0.64) | HTTMAPK1TDP1L3MBTL1LMNA | |
| SCHEMBL5711116 | 0.83 | SLC22A12 (0.67) | HTTMAPK1TDP1L3MBTL1LMNA | |
| SCHEMBL9486597 | 0.82 | HTT (0.87) | HTTMAPK1TDP1L3MBTL1LMNA | |
| SCHEMBL9486161 | 0.81 | HTT (0.62) | HTTMAPK1TDP1L3MBTL1LMNA | |
| SCHEMBL283212 | 0.80 | MAPK1 (0.60) | HTTMAPK1TDP1L3MBTL1GAA | |
| SCHEMBL8624371 | 0.78 | HTT (0.63) | HTTMAPK1TDP1L3MBTL1LMNA | |
| SCHEMBL9486748 | 0.77 | L3MBTL1 (0.63) | HTTMAPK1TDP1L3MBTL1LMNA | |
| SCHEMBL9486652 | 0.76 | HTT (0.64) | HTTMAPK1TDP1L3MBTL1LMNA | |
| SCHEMBL9485478 | 0.76 | ESR1 (0.51) | — | |
| SCHEMBL16540789 | 0.73 | SLC22A12 (0.58) | HTTMAPK1TDP1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2200993-A2 | PROCESS FOR PREPARING BENZOFURANS | Cambrex Karlskoga AB (SE) | 2010-06-30 | — | — | EP | claimed |
| WO-2009044143-A2 | PROCESS FOR PREPARING BENZOFURANS | CAMBREX KARLSKOGA AB (SE) | 2009-04-09 | — | — | WO | claimed |