Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PPM1B | O75688 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3965988 | 0.79 | CYP1A2 (0.39) | CYP1A2HIF1ABRD4ALDH1A1PPM1B | |
| SCHEMBL3972707 | 0.76 | BLM (0.31) | HIF1A | |
| Hydrochloric Acid SCHEMBL3973493 | 0.75 | BLM (0.30) | HIF1A | |
| SCHEMBL1566094 | 0.73 | BRD4 (0.34) | CYP1A2HIF1ABRD4MMP2ANPEP | |
| SCHEMBL3970077 | 0.73 | KMT2A (0.35) | CYP1A2HIF1ABRD4GABRR1MMP2 | |
| SCHEMBL9127247 | 0.72 | CYP1A2 (0.35) | CYP1A2HIF1ABRD4MMP2ANPEP | |
| SCHEMBL9049418 | 0.72 | CYP1A2 (0.35) | CYP1A2HIF1ABRD4MMP2ANPEP | |
| SCHEMBL25761556 | 0.72 | CYP1A2 (0.35) | CYP1A2HIF1ABRD4MMP2ANPEP | |
| SCHEMBL1617863 | 0.70 | TLR4 (0.33) | CYP1A2HIF1ABRD4ALDH1A1PPM1B | |
| SCHEMBL4083564 | 0.69 | CYP1A2 (0.41) | CYP1A2HIF1ABRD4GABRR1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009049018-A1 | NOVEL COMPOUNDS AND METHODS OF USING THEM | SYNDAX PHARMACEUTICALS, INC. (US) | 2009-04-16 | — | — | WO | disclosed |
| WO-2009049018-A1 | NOVEL COMPOUNDS AND METHODS OF USING THEM | SYNDAX PHARMACEUTICALS, INC. (US) | 2009-04-16 | — | — | WO | disclosed |