Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13883366 | 0.77 | SMN1; SMN2 (0.51) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL15517095 | 0.75 | BRD4 (0.39) | CYP1A2HIF1ABRD4MMP2ANPEP | |
| SCHEMBL2484846 | 0.72 | BRD4 (0.37) | CYP1A2HIF1ABRD4CHRM2CHRM4 | |
| SCHEMBL3969491 | 0.69 | CYP1A2 (0.34) | CYP1A2HIF1ABRD4MMP2ANPEP | |
| SCHEMBL1581725 | 0.69 | SMN1; SMN2 (0.47) | BRD4ALDH1A1 | |
| SCHEMBL10586684 | 0.69 | CHRNB2 (0.42) | CYP1A2HIF1ABRD4MMP2ANPEP | |
| SCHEMBL3970077 | 0.68 | KMT2A (0.35) | CYP1A2HIF1ABRD4MMP2ANPEP | |
| SCHEMBL16932134 | 0.67 | CHRM2 (0.38) | CYP1A2HIF1ABRD4CHRM2CHRM4 | |
| SCHEMBL15518785 | 0.67 | CHRM2 (0.38) | CYP1A2HIF1ABRD4CHRM2CHRM4 | |
| SCHEMBL16655183 | 0.66 | SMN1; SMN2 (0.44) | BRD4MMP2ANPEPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009049018-A1 | NOVEL COMPOUNDS AND METHODS OF USING THEM | SYNDAX PHARMACEUTICALS, INC. (US) | 2009-04-16 | — | — | WO | disclosed |