Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 13/20 | 0.59 |
| ▸ | MAOA | P21397 | 2/20 | 0.59 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.59 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.54 |
| ▸ | GRM5 | P41594 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3967618 | 0.86 | PARP15 (0.59) | MAOBMAOAPARP10 | |
| SCHEMBL3970467 | 0.86 | ALOX5 (0.61) | MAOBMAOA | |
| SCHEMBL8935241 | 0.80 | MAOB (0.63) | MAOBMAOAPARP10SCN9ANR4A2 | |
| SCHEMBL7396562 | 0.80 | MAOB (0.71) | MAOBMAOAPARP10SCN9ANR4A2 | |
| SCHEMBL9129876 | 0.80 | MAOB (0.71) | MAOBMAOAPARP10SCN9ANR4A2 | |
| SCHEMBL1067948 | 0.78 | MAOB (0.65) | MAOBMAOAPARP10SCN9ANR4A2 | |
| SCHEMBL8935251 | 0.76 | MAOB (0.58) | MAOBMAOAPARP10SCN9ANR4A2 | |
| SCHEMBL3976085 | 0.76 | MAOB (0.58) | MAOBMAOAPARP10SCN9ANR4A2 | |
| SCHEMBL1070268 | 0.76 | MAOB (0.58) | MAOBMAOAPARP10SCN9ANR4A2 | |
| SCHEMBL19236097 | 0.76 | MAOB (0.63) | MAOBMAOAPARP10SCN9ANR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842143-B3 | 2-(4-SUBSTITUTED)-BENZYLAMINO-2-METHYL-PROPANAMIDE DERIVATIVES | NEWRON PHARM SPA (IT) | 2009-02-18 | — | — | EP | claimed |
| EP-0842143-B1 | 2-(4-SUBSTITUTED)-BENZYLAMINO-2-METHYL-PROPANAMIDE DERIVATIVES | NEWRON PHARM SPA (IT) | 2001-06-13 | — | — | EP | claimed |
| US-5945454-A | 2-(4-substituted)-benzylamino-2-methyl-propanamide derivatives | PHARMACIA & UPJOHN, S.P.A. (IT) | 1999-08-31 | — | — | US | claimed |
| EP-0842143-B3 | 2-(4-SUBSTITUTED)-BENZYLAMINO-2-METHYL-PROPANAMIDE DERIVATIVES | NEWRON PHARM SPA (IT) | 2009-02-18 | — | — | EP | disclosed |
| EP-0842143-B1 | 2-(4-SUBSTITUTED)-BENZYLAMINO-2-METHYL-PROPANAMIDE DERIVATIVES | NEWRON PHARM SPA (IT) | 2001-06-13 | — | — | EP | disclosed |
| US-5945454-A | 2-(4-substituted)-benzylamino-2-methyl-propanamide derivatives | PHARMACIA & UPJOHN, S.P.A. (IT) | 1999-08-31 | — | — | US | disclosed |
| EP-0842143-A1 | 2-(4-SUBSTITUTED)-BENZYLAMINO-2-METHYL-PROPANAMIDE DERIVATIVES | PHARMACIA & UPJOHN S.p.A. (IT) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997005102-A1 | 2-(4-SUBSTITUTED)-BENZYLAMINO-2-METHYL-PROPANAMIDE DERIVATIVES | PHARMACIA & UPJOHN S.P.A. (IT) | 1997-02-13 | — | — | WO | disclosed |