SCHEMBL3969778

SCHEMBL3969778

Oc1cccc(-n2nnc3ccccc32)c1O

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNMA1 Q12791 3/20 0.78
RAB9A P51151 1/20 0.46
POLB P06746 2/20 0.46
ATM Q13315 2/20 0.46
MAPK1 P28482 1/20 0.46
SMN1; SMN2 Q16637 3/20 0.43
MGAM O43451 1/20 0.42
AMY1A P0DUB6 1/20 0.42
GAA P10253 1/20 0.42
SI P14410 1/20 0.42
MGAM2 Q2M2H8 1/20 0.42
DGAT1 O75907 1/20 0.42
KMT2A Q03164 2/20 0.42
SLC9A1 P19634 2/20 0.42
ALDH1A1 P00352 2/20 0.42
KEAP1 Q14145 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL80393 0.88 KCNMA1 (1.00) KCNMA1RAB9APOLBATMMAPK1
SCHEMBL9238836 0.84 KCNMA1 (0.64) KCNMA1RAB9APOLBATMMAPK1
SCHEMBL8445816 0.83 KCNMA1 (0.62) KCNMA1RAB9APOLBATMMAPK1
SCHEMBL19410282 0.80 KCNMA1 (0.59) KCNMA1RAB9APOLBATMMAPK1
SCHEMBL8835833 0.80 KCNMA1 (0.59) KCNMA1RAB9APOLBATMMAPK1
SCHEMBL8431460 0.78 KMT2A (0.59) KCNMA1POLBATMSMN1; SMN2MGAM
SCHEMBL23840194 0.77 KCNMA1 (0.64) KCNMA1RAB9APOLBATMMAPK1
SCHEMBL25862494 0.77 KCNMA1 (0.64) KCNMA1RAB9APOLBATMMAPK1
SCHEMBL9616134 0.77 KCNMA1 (0.55) KCNMA1RAB9APOLBATMMAPK1
SCHEMBL502853 0.76 KCNMA1 (0.67) KCNMA1RAB9APOLBATMMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3565861-B1 PHOTOCURABLE HARDCOAT COMPOSITIONS, METHODS, AND ARTICLES DERIVED THEREFROM BASF SE (DE) 2023-06-21 EP claimed
EP-3344676-B1 CYANATE ESTER DUAL CURE RESINS FOR ADDITIVE MANUFACTURING CARBON INC (US) 2023-04-12 EP claimed
EP-3049464-B1 POLYOLEFIN COMPOSITIONS FOR BUILDING MATERIALS BASF SE (DE) 2020-04-01 EP claimed
EP-2510047-B1 CLARIFIED POLYPROPYLENE ARTICLES WITH IMPROVED OPTICAL PROPERTIES AND/OR INCREASED TEMPERATURE OF CRYSTALLIZATION BASF SE (DE) 2014-11-05 EP claimed
EP-2155815-B1 ANTIMICROBIAL POLYOLEFIN AND POLYESTER COMPOSITIONS BASF SE (DE) 2014-09-03 EP claimed
EP-1620500-B1 PHOTO-CURED AND STABILIZED COATINGS BASF SE (DE) 2012-07-11 EP claimed
EP-1064922-B9 Photoprotective compositions containing a bis-hydroxyphenylbenzotriazole compound and a compound having benzoazolyl or benzodiazolyl groups OREAL (FR) 2009-08-12 EP claimed
EP-1064922-B1 Photoprotective compositions containing a bis-hydroxyphenylbenzotriazole compound and a compound having benzoazolyl or benzodiazolyl groups OREAL (FR) 2005-07-20 EP claimed
EP-1142564-B1 Sunscreen compositions comprising a mixture of polyethylene with a carboxylic function and polyethylene OREAL (FR) 2005-06-15 EP claimed
EP-1167463-B1 Flame retardant resin coating TRESPA INT BV (NL) 2005-04-27 EP claimed
EP-1278718-B1 NOVEL AMINO ACID DERIVATIVES, PREPARATION METHOD, COMPOSITIONS CONTAINING SAME AND USES THEREOF AS SUNSCREENS OREAL (FR) 2003-12-17 EP claimed
US-20030077234-A1 Cosmetic care or makeup composition for a keratin material comprising at least one photoprotective agent and at least one ester comprising an aromatic group L'OREAL. 2003-04-24 US claimed
EP-1254649-A1 Cosmetic compositions comprising an ester and a sunscreen L'OREAL (FR) 2002-11-06 EP claimed
US-6372200-B2 TOPICAL APPLYING SOCIETE L'OREAL S.A. (FR) 2002-04-16 US claimed
US-20010031247-A1 UV-photoprotecting sunscreen compositions comprising immixture of polyethylene/carboxylated polyethylene polymers SOCIETE L'OREAL S.A. (FR) 2001-10-18 US claimed
EP-1142564-A1 Sunscreen compositions comprising a mixture of polyethylene with a carboxylic function and polyethylene L'OREAL (FR) 2001-10-10 EP claimed
US-6296835-B1 SYNERGISTICALLY ENHANCED SUNSCREEN ACTION ON HUMAN SKIN AND/OR HAIR AGAINST DAMAGING EFFECTS OF ULTRAVIOLET-IRRADIATION SOCIETE L'OREAL S.A. (FR) 2001-10-02 US claimed
EP-1064922-A1 Photoprotective compositions containing a bis-hydroxyphenylbenzotriazole compound and a compound having benzoazolyl or benzodiazolyl groups L'OREAL (FR) 2001-01-03 EP claimed
EP-0434618-B1 UV-absorber and light sensible organic material containing it CIBA GEIGY AG (CH) 1995-04-05 EP claimed
EP-0210409-B1 3-AMINOALLYLIDENEMALONONITRILE UV-ABSORBING COMPOUNDS AND PHOTOGRAPHIC ELEMENTS CONTAINING THEM MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-08-19 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030077234-A1 Cosmetic care or makeup composition for a keratin material comprising at least one photoprotective agent and at least one ester comprising an aromatic group KRT18, CUTA, TYR KCNMA1 1860/4885RAB9A 2646/4885POLB 1290/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.