Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PPM1B | O75688 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3970077 | 0.80 | KMT2A (0.35) | CYP1A2HIF1AKMT2ABRD4 | |
| SCHEMBL3965988 | 0.76 | CYP1A2 (0.39) | CYP1A2HIF1APPM1BPTPN1PPP1CC | |
| SCHEMBL13882832 | 0.73 | CYP1A2 (0.46) | CYP1A2HIF1AKMT2APPM1BPTPN1 | |
| SCHEMBL189981 | 0.73 | KMT2A (0.38) | CYP1A2HIF1AKMT2ABRD4 | |
| SCHEMBL3199635 | 0.72 | KMT2A (0.37) | CYP1A2HIF1AKMT2ABRD4 | |
| SCHEMBL5521616 | 0.71 | CYP1A2 (0.41) | CYP1A2HIF1APPM1BPTPN1PPP1CC | |
| SCHEMBL2904103 | 0.70 | KMT2A (0.36) | CYP1A2HIF1AKMT2ABRD4 | |
| SCHEMBL3974812 | 0.70 | CYP1A2 (0.43) | CYP1A2HIF1APPM1BPTPN1PPP1CC | |
| SCHEMBL29929760 | 0.69 | POLB (0.41) | CYP1A2POLB | |
| SCHEMBL1640413 | 0.69 | POLB (0.41) | CYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009049018-A1 | NOVEL COMPOUNDS AND METHODS OF USING THEM | SYNDAX PHARMACEUTICALS, INC. (US) | 2009-04-16 | — | — | WO | disclosed |