Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | BTN3A1 | O00481 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3970116 | 1.00 | TSHR (0.39) | TSHRRECQLPRTN3HDAC3FAAH | |
| SCHEMBL7022520 | 0.97 | NPC1 (0.38) | TSHRPRTN3FAAH | |
| SCHEMBL7024859 | 0.95 | FAAH (0.39) | TSHRFAAH | |
| SCHEMBL7027815 | 0.93 | PRTN3 (0.39) | PRTN3ELANEBTN3A1 | |
| SCHEMBL7771218 | 0.90 | HPGD (0.39) | PRTN3ELANEBTN3A1TDP1 | |
| SCHEMBL7771222 | 0.89 | PPARG (0.40) | TSHRRECQLPRTN3HDAC3FAAH | |
| SCHEMBL873273 | 0.88 | BTN3A1 (0.41) | PRTN3ELANEBTN3A1L3MBTL1 | |
| SCHEMBL3971351 | 0.88 | BTN3A1 (0.41) | PRTN3ELANEBTN3A1L3MBTL1 | |
| SCHEMBL7026839 | 0.86 | ELANE (0.41) | PRTN3ELANE | |
| SCHEMBL7027694 | 0.83 | SMN1; SMN2 (0.41) | TSHRRECQLPRTN3HDAC3ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009052050-A1 | DIOXOLANE THYMINE PHOSPHORAMIDATES AS ANTI-HIV AGENTS | PHARMASSET, INC. (US) | 2009-04-23 | — | — | WO | disclosed |
| US-20090099136-A1 | DIOXOLANE THYMINE PHOSPHORAMIDATES AS ANTI-HIV AGENTS | PHARMASSET, INC. (US) | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099136-A1 | DIOXOLANE THYMINE PHOSPHORAMIDATES AS ANTI-HIV AGENTS | TYMP, DTYMK, TYMS | TSHR 4313/4885RECQL 711/4885PRTN3 583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.