Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 19/20 | 0.61 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3967405 | 0.89 | MTNR1A (0.55) | PLA2G4AMTNR1AMTNR1B | |
| SCHEMBL3969149 | 0.88 | MTNR1A (0.54) | PLA2G4AMTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL3969364 | 0.87 | MTNR1A (0.53) | PLA2G4AMTNR1AMTNR1B | |
| SCHEMBL3972129 | 0.87 | PLA2G4A (0.53) | PLA2G4AMTNR1AMTNR1B | |
| SCHEMBL13883856 | 0.86 | MTNR1A (0.53) | PLA2G4AMTNR1AMTNR1B | |
| SCHEMBL3972972 | 0.85 | MTNR1A (0.52) | PLA2G4AMTNR1AMTNR1B | |
| SCHEMBL3970192 | 0.84 | MTNR1A (0.51) | PLA2G4AMTNR1AMTNR1B | |
| SCHEMBL13884082 | 0.81 | MTNR1A (0.57) | PLA2G4AMTNR1AMTNR1B | |
| SCHEMBL3975921 | 0.81 | MTNR1A (0.48) | PLA2G4AMTNR1AMTNR1B | |
| SCHEMBL13884101 | 0.81 | MTNR1A (0.50) | PLA2G4AMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009047240-A1 | INDOLE DERIVATIVES USEFUL AS PPAR ACTIVATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-04-16 | — | — | WO | disclosed |
| WO-2009047240-A1 | INDOLE DERIVATIVES USEFUL AS PPAR ACTIVATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-04-16 | — | — | WO | disclosed |