Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 19/20 | 0.63 |
| ▸ | PGR | P06401 | 2/20 | 0.49 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.49 |
| ▸ | AR | P10275 | 2/20 | 0.49 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6933442 | 0.84 | NR3C1 (0.90) | NR3C1PGRNR3C2AR | |
| SCHEMBL3965833 | 0.83 | NR3C1 (0.65) | NR3C1PGRNR3C2AR | |
| SCHEMBL4252131 | 0.78 | NR3C1 (0.51) | NR3C1PGRNR3C2AR | |
| SCHEMBL3964719 | 0.77 | NR3C1 (1.00) | NR3C1PGRNR3C2AR | |
| SCHEMBL3966821 | 0.74 | NR3C1 (0.58) | NR3C1PGRNR3C2AR | |
| SCHEMBL1162030 | 0.71 | NR3C1 (0.48) | NR3C1PGRNR3C2AR | |
| SCHEMBL3966896 | 0.71 | NR3C1 (1.00) | NR3C1PGRNR3C2AR | |
| SCHEMBL7178476 | 0.70 | NR3C1 (0.79) | NR3C1PGRNR3C2AR | |
| SCHEMBL3966943 | 0.70 | KMT2A (0.50) | NR3C1PGRNR3C2AR | |
| SCHEMBL1161405 | 0.70 | NR3C1 (0.60) | NR3C1PGRNR3C2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363876-B1 | GLUCOCORTICOID RECEPTOR MODULATORS | KAROBIO AB (SE) | 2009-07-29 | — | — | EP | disclosed |