Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.90 |
| ▸ | PGR | P06401 | 2/20 | 0.74 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.74 |
| ▸ | AR | P10275 | 2/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3964719 | 0.95 | NR3C1 (1.00) | NR3C1PGRNR3C2AR | |
| SCHEMBL3966896 | 0.89 | NR3C1 (1.00) | NR3C1PGRNR3C2AR | |
| SCHEMBL3966679 | 0.86 | NR3C1 (1.00) | NR3C1PGRNR3C2AR | |
| SCHEMBL3969779 | 0.86 | NR3C1 (1.00) | NR3C1PGRNR3C2AR | |
| SCHEMBL7178476 | 0.86 | NR3C1 (0.79) | NR3C1PGRNR3C2AR | |
| SCHEMBL3970344 | 0.84 | NR3C1 (0.85) | NR3C1PGRNR3C2AR | |
| SCHEMBL3966559 | 0.84 | NR3C1 (1.00) | NR3C1PGRNR3C2AR | |
| SCHEMBL3972812 | 0.84 | NR3C1 (0.88) | NR3C1PGRNR3C2AR | |
| SCHEMBL3970747 | 0.84 | NR3C1 (0.63) | NR3C1PGRNR3C2AR | |
| SCHEMBL3970661 | 0.83 | NR3C1 (0.88) | NR3C1PGRNR3C2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363876-A1 | GLUCOCORTICOID RECEPTOR MODULATORS | Abbott Laboratories (US) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002064550-A1 | GLUCOCORTICOID RECEPTOR MODULATORS | ABBOTT LABORATORIES (US) | 2002-08-22 | — | — | WO | disclosed |