Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | F2R | P25116 | 10/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3846570 | 0.99 | KMT2A (0.43) | KMT2AMEN1F2RALOX5PTGS1 | |
| SCHEMBL6938306 | 0.78 | KMT2A (0.46) | KMT2AMEN1F2RALOX5PTGS1 | |
| Bromide SCHEMBL3848630 | 0.77 | KMT2A (0.45) | KMT2AMEN1F2RALOX5PTGS1 | |
| SCHEMBL3964631 | 0.76 | KMT2A (0.44) | KMT2AMEN1F2RALOX5PTGS1 | |
| Bromide SCHEMBL3853603 | 0.75 | KMT2A (0.43) | KMT2AMEN1F2RALOX5PTGS1 | |
| SCHEMBL3960925 | 0.74 | KMT2A (0.44) | KMT2AMEN1F2RALOX5PTGS1 | |
| Bromide SCHEMBL3853733 | 0.73 | KMT2A (0.43) | KMT2AMEN1F2RALOX5PTGS1 | |
| SCHEMBL6932935 | 0.73 | F2R (0.48) | KMT2AMEN1F2RALOX5PTGS1 | |
| Bromide SCHEMBL3892815 | 0.72 | KMT2A (0.48) | KMT2AMEN1F2RALOX5PTGS1 | |
| SCHEMBL6937786 | 0.72 | CYP3A4 (0.42) | KMT2AMEN1F2RALOX5PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808163-B1 | USE OF THIAZOLIUM COMPOUNDS FOR PREVENTING AND REVERSING THE FORMATION OF ADVANCED GLYCOSYLATION ENDPRODUCTS | ALTEON INC (US) | 2003-07-23 | — | — | EP | claimed |
| US-6440749-B1 | ADMINISTERING A THIAZOLE COMPOUND | ALTEON. INC. | 2002-08-27 | — | — | US | claimed |
| US-6007865-A | FOR INHIBITING AND REVERSING NONENZYMATIC CROSS-LINKING (PROTEIN AGING), TREATING KIDNEY DAMAGE AND TREATING COMPLICATIONS OF DIABETES, PREVENTING FOOD SPOILAGE | ALTEON INC. | 1999-12-28 | — | — | US | claimed |
| WO-2009042213-A1 | METHODS OF TREATING OR PREVENTING CARDIAC DISEASE ASSOCIATED WITH A HIGH FAT DIET | SYNVISTA THERAPEUTICS, INC. (US) | 2009-04-02 | — | — | WO | disclosed |