Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | F2R | P25116 | 9/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3853734 | 0.99 | CYP3A4 (0.42) | CYP3A4MEN1KMT2AF2RALOX5 | |
| SCHEMBL3964631 | 0.84 | KMT2A (0.44) | CYP3A4MEN1KMT2AF2RALOX5 | |
| Bromide SCHEMBL3853603 | 0.83 | KMT2A (0.43) | CYP3A4MEN1KMT2AF2RALOX5 | |
| Bromide SCHEMBL5015890 | 0.78 | KMT2A (0.41) | CYP3A4MEN1KMT2AF2RALOX5 | |
| SCHEMBL6937918 | 0.78 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL6935010 | 0.76 | RAB9A (0.43) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| Bromide SCHEMBL3957516 | 0.75 | RAB9A (0.45) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL3960925 | 0.74 | KMT2A (0.44) | CYP3A4MEN1KMT2AF2RALOX5 | |
| SCHEMBL6935377 | 0.74 | ALDH1A1 (0.52) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| Bromide SCHEMBL3853733 | 0.73 | KMT2A (0.43) | CYP3A4MEN1KMT2AF2RALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808163-B1 | USE OF THIAZOLIUM COMPOUNDS FOR PREVENTING AND REVERSING THE FORMATION OF ADVANCED GLYCOSYLATION ENDPRODUCTS | ALTEON INC (US) | 2003-07-23 | — | — | EP | claimed |