Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 10/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3844602 | 0.99 | F2R (0.47) | F2RMAOBSLC22A12ALOX5PTGS1 | |
| SCHEMBL6939772 | 0.79 | ALDH1A1 (0.46) | MEN1KMT2ABCHEACHE | |
| Bromide SCHEMBL27893556 | 0.78 | ALDH1A1 (0.48) | MEN1KMT2ABCHEACHE | |
| Bromide SCHEMBL2954116 | 0.78 | ALDH1A1 (0.48) | MEN1KMT2ABCHEACHE | |
| SCHEMBL3964631 | 0.78 | KMT2A (0.44) | F2RALOX5PTGS1PTGS2MEN1 | |
| Bromide SCHEMBL3853603 | 0.77 | KMT2A (0.43) | F2RALOX5PTGS1PTGS2MEN1 | |
| SCHEMBL6939314 | 0.75 | GSK3B (0.47) | KMT2ABCHE | |
| SCHEMBL6937921 | 0.74 | MAPT (0.53) | BCHEACHE | |
| Bromide SCHEMBL3854344 | 0.74 | MAPT (0.48) | BCHE | |
| SCHEMBL6937786 | 0.73 | CYP3A4 (0.42) | F2RALOX5PTGS1PTGS2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808163-B1 | USE OF THIAZOLIUM COMPOUNDS FOR PREVENTING AND REVERSING THE FORMATION OF ADVANCED GLYCOSYLATION ENDPRODUCTS | ALTEON INC (US) | 2003-07-23 | — | — | EP | claimed |
| US-6440749-B1 | ADMINISTERING A THIAZOLE COMPOUND | ALTEON. INC. | 2002-08-27 | — | — | US | claimed |