Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MLYCD | O95822 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | USP5 | P45974 | 1/20 | 0.41 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3763908 | 0.87 | KDM4E (0.50) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL21141800 | 0.87 | LMNA (0.51) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL13505994 | 0.87 | LMNA (0.51) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL104285 | 0.77 | HPGD (0.63) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL12089760 | 0.77 | RAB9A (0.46) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL30729582 | 0.75 | KMT2A (0.43) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL21141808 | 0.74 | POLB (0.50) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL21141804 | 0.74 | POLB (0.50) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL13505949 | 0.74 | POLB (0.50) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL22618725 | 0.74 | RAB9A (0.56) | RAB9ASMN1; SMN2NPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009047240-A1 | INDOLE DERIVATIVES USEFUL AS PPAR ACTIVATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-04-16 | — | — | WO | disclosed |