Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 10/20 | 0.56 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.56 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.56 |
| ▸ | CA2 | P00918 | 3/20 | 0.56 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.56 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | FAAH | O00519 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.56 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6752473 | 0.94 | GABRA1 (0.50) | GABRA1GABRB2GABRB1CA2GABRG2 | |
| SCHEMBL430924 | 0.79 | GABRA1 (0.58) | GABRA1GABRB2GABRB1CA2GABRG2 | |
| SCHEMBL8957734 | 0.74 | GABRA1 (0.52) | GABRA1GABRB2GABRB1CA2GABRG2 | |
| Propofol SCHEMBL2414429 | 0.72 | GABRA1 (1.00) | GABRA1GABRB2GABRB1CA2GABRG2 | |
| Propofol SCHEMBL36245 | 0.72 | GABRA1 (1.00) | GABRA1GABRB2GABRB1CA2GABRG2 | |
| SCHEMBL25071130 | 0.71 | HIF1A (0.44) | TSHRCYP1A2CYP3A4LMNAHPGD | |
| SCHEMBL1685326 | 0.71 | GABRA1 (0.65) | GABRA1GABRB2GABRB1CA2GABRG2 | |
| Propofol SCHEMBL1033835 | 0.70 | GABRA1 (0.94) | GABRA1GABRB2GABRB1CA2GABRG2 | |
| Propofol SCHEMBL10968613 | 0.70 | GABRA1 (0.94) | GABRA1GABRB2GABRB1CA2GABRG2 | |
| Propofol SCHEMBL8935177 | 0.70 | GABRA1 (0.94) | GABRA1GABRB2GABRB1CA2GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504543-B2 | Polyether alcohols and method for the production of polyether alcohols for polyurethane synthesis | BASF AKTIENGESELLSCHAFT (DE) | 2009-03-17 | — | — | US | disclosed |
| US-7470735-B2 | Phenol-free phosphites | DOVER CHEMICAL CORPORATION (US) | 2008-12-30 | — | — | US | disclosed |
| US-20070173628-A1 | Polyether alcohols and method for the production of polyether alcohols for polyurethane synthesis | BASF AKTIENGESELLSCHAFT (DE) | 2007-07-26 | — | — | US | disclosed |
| WO-2005113665-A2 | PHENOL-FREE PHOSPHITES | DOVER CHEMICAL CORPORATION (US) | 2005-12-01 | — | — | WO | disclosed |
| US-20040242437-A1 | Antiwear performance of engine oils with $g(b)-dithiophosphorylated propionic acids | CIBA SPECIALTY CHEMICALS CORP. | 2004-12-02 | — | — | US | disclosed |
| US-20040180999-A1 | PHENOL-FREE PHOSPHITES | DOVER CHEMICAL CORPORATION (US) | 2004-09-16 | — | — | US | disclosed |
| US-5077340-A | Ethylenically unsaturated compounds containing 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidine moieties, and polymers, copolymers and stabilized compositions | CIBA-GEIGY CORPORATION (US) | 1991-12-31 | — | — | US | disclosed |