Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HK1 | P19367 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1055485 | 0.96 | CHRNB4 (0.43) | CHRNB4CHRNA3ALDH1A1RAB9ANPC1 | |
| SCHEMBL13832933 | 0.87 | CHRNB4 (0.40) | CHRNB4CHRNA3ALDH1A1RAB9ANPC1 | |
| SCHEMBL968176 | 0.86 | CHRNB4 (0.46) | CHRNB4CHRNA3ALDH1A1RAB9ANPC1 | |
| SCHEMBL971143 | 0.84 | CHRNB4 (0.49) | CHRNB4CHRNA3ALDH1A1RAB9ANPC1 | |
| SCHEMBL19027906 | 0.84 | CHRNB4 (0.38) | CHRNB4CHRNA3ALDH1A1RAB9ANPC1 | |
| SCHEMBL15823144 | 0.83 | CHRNB4 (0.47) | CHRNB4CHRNA3ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL18562454 | 0.79 | CHRNB4 (0.40) | CHRNB4CHRNA3ALDH1A1RAB9ANPC1 | |
| SCHEMBL932928 | 0.77 | PIK3CD (0.45) | CHRNB4CHRNA3ALDH1A1RAB9ANPC1 | |
| SCHEMBL904011 | 0.77 | HTR2C (0.66) | — | |
| SCHEMBL29546450 | 0.75 | ALDH1A1 (0.52) | CHRNB4CHRNA3ALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122036805-A | Compound containing phosphaphenanthrene bonded benzocyclobutene, and preparation method and application thereof | 武汉迪赛环保新材料股份有限公司 | 2026-05-15 | — | — | CN | disclosed |
| CN-118271184-A | Dendritic structural compound, compound thereof and organic electroluminescent device | 中国科学院长春应用化学研究所 | 2024-07-02 | — | — | CN | disclosed |
| CN-115417773-B | Dendritic structural compound, compound thereof and organic electroluminescent device | 中国科学院长春应用化学研究所 | 2024-05-28 | — | — | CN | disclosed |
| CN-115417773-A | Dendritic structure compound and compound thereof, and organic electroluminescent device | 中国科学院长春应用化学研究所 | 2022-12-02 | — | — | CN | disclosed |
| US-20220199906-A1 | POLYMER FOR ORGANIC ELECTROLUMINESCENT ELEMENTS AND ORGANIC ELECTROLUMINESCENT ELEMENT | NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) | 2022-06-23 | — | — | US | disclosed |
| CN-106543002-B | Aryl cyclobutene | 陶氏环球技术有限责任公司 | 2022-06-17 | — | — | CN | disclosed |
| EP-3950767-A1 | POLYMER FOR ORGANIC ELECTROLUMINESCENT ELEMENTS AND ORGANIC ELECTROLUMINESCENT ELEMENT | NIPPON STEEL Chemical & Material Co., Ltd. (JP) | 2022-02-09 | — | — | EP | disclosed |
| CN-113631626-A | Polymer for organic electroluminescent element and organic electroluminescent element | 日铁化学材料株式会社 | 2021-11-09 | — | — | CN | disclosed |
| WO-2020203203-A1 | POLYMER FOR ORGANIC ELECTROLUMINESCENT ELEMENTS AND ORGANIC ELECTROLUMINESCENT ELEMENT | 日鉄ケミカル＆マテリアル株式会社 | 2020-10-08 | — | — | WO | disclosed |
| US-10030165-B2 | Arylcyclobutenes | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-07-24 | — | — | US | disclosed |
| US-5422410-A | Heating the polymerized vinylbenzocyclobutene with styrene monomer, decyclizing the cyclobutene side ring to form chain extension and crosslinking | THE DOW CHEMICAL COMPANY (US) | 1995-06-06 | — | — | US | disclosed |
| US-5391650-A | Amorphous, low viscosity and self-curing; workability; molding materials; composites; adhesives; binders; coatings; heat resistance | THE DOW CHEMICAL COMPANY (US) | 1995-02-21 | — | — | US | disclosed |
| WO-1994025903-A1 | PARTIALLY POLYMERIZED RESINS | THE DOW CHEMICAL COMPANY (US) | 1994-11-10 | — | — | WO | disclosed |
| US-5120884-A | Preparation of hydroxy arylcyclobutenes | THE DOW CHEMICAL COMPANY (US) | 1992-06-09 | — | — | US | disclosed |
| US-5002808-A | Adhesion methods employing benzocyclobutene-based organosilane adhesion aids | THE DOW CHEMICAL COMPANY (US) | 1991-03-26 | — | — | US | disclosed |
| US-4898999-A | Process for halogenating cyclobutenoarenes | SHELL OIL COMPANY (US) | 1990-02-06 | — | — | US | disclosed |
| EP-0346959-A1 | Process for halogenating cyclobutenoarenes | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-12-20 | — | — | EP | disclosed |
| WO-1989009658-A1 | BENZOCYCLOBUTENE-BASED ORGANOSILANE ADHESION AIDS | THE DOW CHEMICAL COMPANY (US) | 1989-10-19 | — | — | WO | disclosed |
| EP-0334269-A2 | Benzocyclobutene-based organosilane adhesion aids | THE DOW CHEMICAL COMPANY (US) | 1989-09-27 | — | — | EP | disclosed |
| US-4831172-A | Benzocyclobutene-based organosilane adhesion aids | THE DOW CHEMICAL COMPANY (US) | 1989-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10030165-B2 | Arylcyclobutenes | NOD2, GNE, BMI1 | CHRNB4 470/4885CHRNA3 1054/4885ALDH1A1 2253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.