Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | GMNN | O75496 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.34 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31273013 | 0.97 | ALDH1A1 (0.35) | ALDH1A1MAPTCA12GMNNCA1 | |
| SCHEMBL5067660 | 0.94 | ALDH1A1 (0.41) | ALDH1A1MAPTCA12GMNNCA1 | |
| SCHEMBL3765866 | 0.88 | ALDH1A1 (0.37) | ALDH1A1EPAS1 | |
| SCHEMBL31501282 | 0.88 | MAPT (0.36) | ALDH1A1MAPTCA12GMNNCA1 | |
| SCHEMBL9823006 | 0.88 | — | — | |
| SCHEMBL30487174 | 0.88 | MAPT (0.39) | ALDH1A1MAPTCA12GMNNCA1 | |
| SCHEMBL6682956 | 0.87 | ALDH1A1 (0.43) | ALDH1A1MAPTCA12GMNNCA1 | |
| SCHEMBL31406992 | 0.87 | — | — | |
| SCHEMBL2011115 | 0.84 | ALDH1A1 (0.35) | ALDH1A1MAPTCA12GMNNCA1 | |
| SCHEMBL11848572 | 0.83 | ALDH1A1 (0.50) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1790629-B1 | Derivatives of octahydro-cycloprop-indene and their use in perfume compositions | INT FLAVORS & FRAGRANCES INC (US) | 2013-07-03 | — | — | EP | disclosed |
| US-7482317-B2 | Derivatives of decahydro-cycloprop[e]indene compounds and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2009-01-27 | — | — | US | disclosed |
| US-7482317-B2 | Derivatives of decahydro-cycloprop[e]indene compounds and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2009-01-27 | — | — | US | disclosed |
| US-20070225200-A1 | DERIVATIVES OF DECAHYDRO-CYCLOPROP[E]INDENE COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2007-09-27 | — | — | US | disclosed |
| US-7232795-B2 | Derivatives of decahydro-cycloprop[e]indene compounds and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2007-06-19 | — | — | US | disclosed |
| US-7232795-B2 | Derivatives of decahydro-cycloprop[e]indene compounds and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2007-06-19 | — | — | US | disclosed |
| EP-1790629-A1 | Derivatives of octahydro-cycloprop-indene and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES, INC. (US) | 2007-05-30 | — | — | EP | disclosed |
| US-20070117727-A1 | DERIVATIVES OF DECAHYDRO-CYCLOPROP[E]INDENE COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2007-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070117727-A1 | DERIVATIVES OF DECAHYDRO-CYCLOPROP[E]INDENE COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | CPT1A, CYP8B1, DECR1 | ALDH1A1 410/4885MAPT 3148/4885CA12 2596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.