Furan

Furan

SCHEMBL3971337

O=C(S)C1CC1.c1ccoc1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL193591 0.79
Furan SCHEMBL3971336 0.68 MAPK1 (0.40) MAPK1TDP1
SCHEMBL1573722 0.68
SCHEMBL3978415 0.68
SCHEMBL17733823 0.67 PLG (0.31)
SCHEMBL5472170 0.67
Furan SCHEMBL5278070 0.67 MAPK1 (0.61) MAPK1TDP1
Furan SCHEMBL7296766 0.67
Furan SCHEMBL27656052 0.67 MAPK1 (0.61) MAPK1TDP1
Furan SCHEMBL7102357 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7524885-B2 Compounds that stimulate glucose utilization and methods of use THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2009-04-28 US disclosed
US-20050182133-A1 Compounds that stimulate glucose utilization and methods of use UNIVERSITY OF ALBERTA (CA) 2005-08-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050182133-A1 Compounds that stimulate glucose utilization and methods of use GPR119, SLC2A4, SLC2A1 MAPK1 598/4885TDP1 4278/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.