⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1573722 | 0.86 | — | — | |
| SCHEMBL3978415 | 0.86 | — | — | |
| SCHEMBL17733823 | 0.85 | PLG (0.31) | — | |
| SCHEMBL9336166 | 0.83 | CES2 (0.58) | — | |
| Methane SCHEMBL27674322 | 0.83 | CES2 (0.58) | — | |
| SCHEMBL1573811 | 0.83 | — | — | |
| Furan SCHEMBL3971337 | 0.79 | MAPK1 (0.38) | — | |
| SCHEMBL5472170 | 0.78 | — | — | |
| SCHEMBL12467340 | 0.78 | — | — | |
| SCHEMBL18782819 | 0.74 | ALDH1A1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1868982-B1 | COMPOUNDS THAT STIMULATE GLUCOSE UTILIZATION AND METHODS OF USE | UNIV ALBERTA (CA) | 2015-04-29 | — | — | EP | claimed |
| JP-4764888-B2 | — | — | 2011-09-07 | — | — | JP | claimed |
| US-20090258835-A1 | COMPOUNDS THAT STIMULATE GLUCOSE UTILIZATION AND METHODS OF USE | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA TEC EDMONTON (CA) | 2009-10-15 | — | — | US | claimed |
| US-7524885-B2 | Compounds that stimulate glucose utilization and methods of use | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2009-04-28 | — | — | US | claimed |
| EP-1868982-A2 | COMPOUNDS THAT STIMULATE GLUCOSE UTILIZATION AND METHODS OF USE | The Governors of the University of Alberta (CA) | 2007-12-26 | — | — | EP | claimed |
| JP-2007528404-A | — | — | 2007-10-11 | — | — | JP | claimed |
| EP-1734942-A1 | SUBSTITUTED UREA AND CARBAMATE, PHENACYL-2-HYDROXY-3-DIAMINOALKANE, AND BENZAMIDE-2-HYDROXY-3-DIAMINOALKANE ASPARTYL-PROTEASE INHIBITORS | ELAN PHARMACEUTICALS, INC. (US) | 2006-12-27 | — | — | EP | claimed |
| WO-2006117686-A2 | COMPOUNDS THAT STIMULATE GLUCOSE UTILIZATION AND METHODS OF USE | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2006-11-09 | — | — | WO | claimed |
| US-20050261273-A1 | Substituted urea and carbamate, phenacyl-2-hydroxy-3-diaminoalkane, and benzamide-2-hydroxy-3-diaminoalkane aspartyl-protease inhibitors | ELAN PHARMACEUTICALS, INC. | 2005-11-24 | — | — | US | claimed |
| WO-2005087215-A1 | SUBSTITUTED UREA AND CARBAMATE, PHENACYL-2-HYDROXY-3-DIAMINOALKANE, AND BENZAMIDE-2-HYDROXY-3-DIAMINOALKANE ASPARTYL-PROTEASE INHIBITORS | ELAN PHARMACEUTICALS, INC. (US) | 2005-09-22 | — | — | WO | claimed |
| US-20050182133-A1 | Compounds that stimulate glucose utilization and methods of use | UNIVERSITY OF ALBERTA (CA) | 2005-08-18 | — | — | US | claimed |
| US-4112116-A | Certain cyclopropane thiolcarboxylates and use thereof as miticides | STAUFFER CHEMICAL COMPANY (US) | 1978-09-05 | — | — | US | claimed |
| CN-112512529-B | Cyclopentenepurine derivative or salt thereof | 富士胶片株式会社 | 2024-06-18 | — | — | CN | disclosed |
| EP-3831388-B1 | CYCLOPENTENYL PURINE DERIVATIVE OR SALT THEREOF FOR USE IN SUPPRESSING ADENOVIRUS | FUJIFILM CORP (JP) | 2024-02-28 | — | — | EP | disclosed |
| US-20230312474-A1 | PHENOL DERIVATIVE | Sumitomo Pharma Co., Ltd. (JP) | 2023-10-05 | — | — | US | disclosed |
| US-20230295202-A1 | CYCLOBUTYL PURINE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2023-09-21 | — | — | US | disclosed |
| EP-0003960-B1 | 6-SUBSTITUTED THIA-AZA-COMPOUNDS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CIBA-GEIGY AG (CH) | 1983-06-29 | — | — | EP | disclosed |
| EP-0042026-A1 | 3,4-Disubstituted azetidin-2-on compounds and process for their preparation | CIBA-GEIGY AG (CH) | 1981-12-23 | — | — | EP | disclosed |
| EP-0003960-A1 | 6-Substituted thia-aza-compounds, their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1979-09-19 | — | — | EP | disclosed |
| US-4112116-A | Certain cyclopropane thiolcarboxylates and use thereof as miticides | STAUFFER CHEMICAL COMPANY (US) | 1978-09-05 | — | — | US | disclosed |