Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glycinebetaine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | CPT2 | P23786 | 1/20 | 0.40 |
| ▸ | CPT1A | P50416 | 1/20 | 0.40 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycinebetaine SCHEMBL3799637 | 0.83 | EPHX2 (0.38) | EPHX2CPT2CPT1ACPT1BCA2 | |
| SCHEMBL917335 | 0.82 | ALDH1A1 (0.56) | EPHX2CA1CA2RELA | |
| SCHEMBL917965 | 0.82 | ALDH1A1 (0.56) | EPHX2CA1CA2RELA | |
| SCHEMBL918031 | 0.82 | ALDH1A1 (0.56) | EPHX2CA1CA2RELA | |
| SCHEMBL917918 | 0.82 | ALDH1A1 (0.56) | EPHX2CA1CA2RELA | |
| SCHEMBL918712 | 0.82 | ALDH1A1 (0.56) | EPHX2CA1CA2RELA | |
| SCHEMBL918208 | 0.82 | ALDH1A1 (0.56) | EPHX2CA1CA2RELA | |
| SCHEMBL917570 | 0.82 | ALDH1A1 (0.56) | EPHX2CA1CA2RELA | |
| SCHEMBL918549 | 0.82 | ALDH1A1 (0.56) | EPHX2CA1CA2RELA | |
| SCHEMBL917576 | 0.82 | ALDH1A1 (0.56) | EPHX2CA1CA2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054486-A2 | FRICTION REDUCTION FLUIDS | Services Pétroliers Schlumberger (FR) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008020388-A2 | FRICTION REDUCTION FLUIDS | SCHLUMBERGER CANADA LIMITED (CA) | 2008-02-21 | — | — | WO | disclosed |