Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | ALB | P02768 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | CCKBR | P32239 | 11/20 | 0.63 |
| ▸ | CCKAR | P32238 | 4/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4819173 | 0.97 | MEN1 (0.69) | MEN1LMNAALBKMT2ACCKBR | |
| Cyclohexane SCHEMBL3964908 | 0.91 | CCKBR (0.62) | MEN1LMNAALBKMT2ACCKBR | |
| SCHEMBL643212 | 0.88 | MEN1 (0.58) | MEN1LMNAALBKMT2ACCKBR | |
| SCHEMBL641962 | 0.88 | MEN1 (0.66) | MEN1LMNAALBKMT2ACCKBR | |
| Cyclohexane SCHEMBL3966556 | 0.86 | CCKBR (0.71) | CCKBRCCKAR | |
| SCHEMBL4701636 | 0.86 | LMNA (0.68) | MEN1LMNAALBKMT2ACCKBR | |
| SCHEMBL3969425 | 0.85 | MEN1 (0.55) | MEN1LMNAALBKMT2ACCKBR | |
| SCHEMBL5418531 | 0.85 | LMNA (0.72) | MEN1LMNAALBKMT2ACCKBR | |
| SCHEMBL643974 | 0.85 | CHRM1 (0.65) | MEN1LMNAALBKMT2ACCKBR | |
| SCHEMBL11899990 | 0.84 | CCKBR (0.78) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1727550-B1 | PHARMACEUTICAL COMPOSITION COMPRISING A BENZODIAZEPINE DERIVATIVE AND AN INHIBITOR OF THE RSV FUSION PROTEIN | ARROW THERAPEUTICS LTD (GB) | 2009-07-29 | — | — | EP | claimed |