Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.49 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4670702 | 0.89 | ALDH1A1 (0.56) | ALDH1A1MAPTHPGDMAPK1GAA | |
| SCHEMBL5995027 | 0.88 | HPGD (0.57) | ALDH1A1MAPTHPGDMAPK1GAA | |
| SCHEMBL3971826 | 0.88 | ALDH1A1 (0.48) | ALDH1A1MAPTHPGDMAPK1GAA | |
| SCHEMBL3970328 | 0.87 | ALDH1A1 (0.55) | ALDH1A1MAPTHPGDMAPK1GAA | |
| SCHEMBL4670233 | 0.83 | ALDH1A1 (0.56) | ALDH1A1MAPTHPGDMAPK1GAA | |
| SCHEMBL3972889 | 0.82 | HPGD (0.51) | ALDH1A1MAPTHPGDMAPK1GAA | |
| SCHEMBL2858114 | 0.82 | HPGD (0.57) | ALDH1A1MAPTHPGDMAPK1GAA | |
| SCHEMBL3977382 | 0.82 | KDM4E (0.58) | ALDH1A1MAPTHPGDPOLBMAPK14 | |
| SCHEMBL2857376 | 0.81 | ALDH1A1 (0.67) | ALDH1A1MAPTHPGDMAPK1GAA | |
| SCHEMBL4672609 | 0.81 | CCR1 (0.50) | ALDH1A1MAPTHPGDMAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7534894-B2 | Biphenyloxy-acids | WYETH (US) | 2009-05-19 | — | — | US | claimed |
| US-20060020003-A1 | Biphenyloxy-acids | WYETH (US) | 2006-01-26 | — | — | US | claimed |
| US-7534894-B2 | Biphenyloxy-acids | WYETH (US) | 2009-05-19 | — | — | US | disclosed |
| EP-1667959-A1 | BIPHENYLOXY-ACIDS | Wyeth (US) | 2006-06-14 | — | — | EP | disclosed |
| US-20060020003-A1 | Biphenyloxy-acids | WYETH (US) | 2006-01-26 | — | — | US | disclosed |
| WO-2005030702-A1 | BIPHENYLOXY-ACIDS | WYETH (US) | 2005-04-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060020003-A1 | Biphenyloxy-acids | AHR, ARNT, NR1H4 | ALDH1A1 388/4885MAPT 4702/4885HPGD 2936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.