SCHEMBL3971595

SCHEMBL3971595

Cc1cc(CCc2cc(C)cc(C(C)(C)C)c2OCl)c(OCl)c(C(C)(C)C)c1.[Ti]

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.43
CYP2C9 P11712 2/20 0.43
CYP2C19 P33261 2/20 0.43
HIF1A Q16665 2/20 0.43
ALDH1A1 P00352 1/20 0.39
CA2 P00918 1/20 0.39
POLB P06746 1/20 0.39
TYR P14679 1/20 0.39
CYP2D6 P10635 2/20 0.39
HSD17B10 Q99714 1/20 0.39
CYP3A4 P08684 1/20 0.36
HTR2A P28223 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1777835 0.89 HSPA5 (0.53) HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A
SCHEMBL8635197 0.79 HSPA5 (0.46) HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A
Hydrochloric Acid SCHEMBL28141949 0.79 SMN1; SMN2 (0.46) HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A
SCHEMBL2873270 0.75 SMN1; SMN2 (0.39) HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A
SCHEMBL28034278 0.74 SMN1; SMN2 (0.50) HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A
Hydrochloric Acid SCHEMBL27797444 0.72 SMN1; SMN2 (0.48) HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A
Hydrochloric Acid SCHEMBL27786111 0.72 SMN1; SMN2 (0.48) HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A
Hydrochloric Acid SCHEMBL10482156 0.72 SMN1; SMN2 (0.48) HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A
SCHEMBL1777908 0.72 SMN1; SMN2 (0.37) HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A
SCHEMBL6567754 0.70 HSPA5 (0.44) HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7524789-B2 Process for producing modified particle, carrier or catalyst component for addition polymerization, pre-polymerized catalyst component therefor, catalyst therefor, and addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-04-28 US disclosed
US-20080234450-A1 DIENE POLYMER AND PROCESS FOR PRODUCING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-25 US disclosed
US-7410925-B2 Metal compound, and catalyst component and catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-08-12 US disclosed
US-7186667-B2 Catalyst component and catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-03-06 US disclosed
US-7122691-B2 Process for producing compound, catalyst component for addition polymerization, process for producing catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-10-17 US disclosed
US-20060030480-A1 Metal compound, and catalyst component and catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2006-02-09 US disclosed
US-20050245701-A1 Process for producing modified particle; carrier; catalyst component for addition polymerization; process for producing catalyst for addition polymerization; and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2005-11-03 US disclosed
US-20050222351-A1 Process for producing compound, catalyst component for addition polymerization, process for producing catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2005-10-06 US disclosed
US-20050148459-A1 Process for producing modified particle, carrier or catalyst component for addition polymerization, pre-polymerized catalyst component therefor, catalyst therefor, and addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2005-07-07 US disclosed
US-20040209767-A1 Contact product, and catalyst component and catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2004-10-21 US disclosed
US-20040186009-A1 Catalyst component and catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-09-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050222351-A1 Process for producing compound, catalyst component for addition polymerization, process for producing catalyst for addition polymerization, and process for producing addition polymer CCNT1, C5, C9 HSPA5 4750/4885SMN1; SMN2 3859/4885CYP2C9 533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.