Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 8/20 | 0.65 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | VCP | P55072 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3977673 | 0.86 | ABL1 (0.62) | ABL1XIAPALOX5VCPNPC1 | |
| SCHEMBL24590269 | 0.80 | NPY5R (0.57) | ALOX5NPC1RAB9AMEN1KMT2A | |
| SCHEMBL19625338 | 0.79 | ABL1 (0.55) | ABL1XIAPNPC1RAB9AMEN1 | |
| SCHEMBL19627004 | 0.77 | ABL1 (0.59) | ABL1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL25242184 | 0.75 | RAB9A (0.61) | ABL1ALOX5NPC1RAB9AMEN1 | |
| SCHEMBL24590258 | 0.75 | ALOX5 (0.56) | ALOX5NPC1RAB9AMEN1KMT2A | |
| SCHEMBL4077412 | 0.75 | ABL1 (0.57) | ABL1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL24590319 | 0.74 | ALOX5 (0.59) | ALOX5VCPNPC1RAB9AMEN1 | |
| SCHEMBL24590248 | 0.74 | MEN1 (0.64) | ALOX5NPC1RAB9AMEN1KMT2A | |
| SCHEMBL24590270 | 0.74 | MAPT (0.62) | ALOX5VCPNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054410-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | Wyeth (US) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008021331-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | WYETH (US) | 2008-02-21 | — | — | WO | disclosed |