SCHEMBL3971766

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3972236	0.87	SMN1; SMN2 (0.50)	ALDH1A1POLBNPC1RAB9AKDM4E
	SCHEMBL3968565	0.83	NR1H4 (0.67)	NR1H4HPSEALDH1A1POLBKDM4E
	SCHEMBL3970052	0.81	ALDH1A1 (0.58)	NR1H4HPSEALDH1A1POLBNPC1
	SCHEMBL963654	0.74	ATM (0.54)	POLBKDM4ENLRP3ATM
	SCHEMBL3973956	0.72	SMN1; SMN2 (0.57)	NR1H4ALDH1A1POLBNPC1RAB9A
	SCHEMBL3972228	0.71	SMN1; SMN2 (0.56)	ALDH1A1POLBNPC1RAB9AKDM4E
	SCHEMBL27658312	0.71	NR1H4 (0.52)	NR1H4ALDH1A1POLBNPC1RAB9A
	SCHEMBL30455793	0.71	PGR (0.66)	ALDH1A1POLBNPC1RAB9AKDM4E
	SCHEMBL3972201	0.70	ALDH1A1 (0.53)	HPSEALDH1A1NPC1RAB9AKMT2A
	SCHEMBL11739989	0.69	PTGS1 (0.66)	NR1H4HPSEALDH1A1POLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.