Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 20/20 | 0.52 |
| ▸ | HRH1 | P35367 | 5/20 | 0.52 |
| ▸ | HTR2B | P41595 | 2/20 | 0.52 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3977762 | 0.90 | SSTR5 (0.52) | SSTR5HRH1HTR2B | |
| SCHEMBL3997486 | 0.86 | SSTR5 (0.52) | SSTR5HRH1HTR2BSSTR1KCNH2 | |
| SCHEMBL3974044 | 0.85 | SSTR5 (0.48) | SSTR5HRH1HTR2BSSTR1KCNH2 | |
| SCHEMBL3973407 | 0.82 | SSTR5 (0.47) | SSTR5HRH1HTR2BSSTR1KCNH2 | |
| SCHEMBL4082633 | 0.80 | SSTR5 (0.43) | SSTR5HRH1HTR2BSSTR1KCNH2 | |
| SCHEMBL3972791 | 0.78 | SSTR5 (0.51) | SSTR5HRH1HTR2B | |
| SCHEMBL3974073 | 0.78 | SSTR5 (0.51) | SSTR5HRH1HTR2BSSTR1KCNH2 | |
| SCHEMBL3977776 | 0.78 | SSTR5 (0.50) | SSTR5HRH1HTR2B | |
| SCHEMBL2419789 | 0.77 | SSTR5 (0.69) | SSTR5HRH1HTR2BSSTR1KCNH2 | |
| SCHEMBL2419779 | 0.77 | SSTR5 (0.69) | SSTR5HRH1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054385-A2 | PHENYL, PYRIDINE AND QUINOLINE DERIVATIVES | F. Hoffmann-Roche AG (CH) | 2009-05-06 | — | — | EP | claimed |
| WO-2008019967-A2 | PHENYL, PYRIDINE AND QUINOLINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-02-21 | — | — | WO | claimed |