Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT3 | Q9NTG7 | 10/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.47 |
| ▸ | KDM5A | P29375 | 1/20 | 0.45 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.45 |
| ▸ | EYA3 | Q99504 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3968618 | 0.82 | SIRT3 (0.57) | SIRT3NR1H4PTPN1KDM5AKDM7A | |
| SCHEMBL3972664 | 0.82 | PTPN1 (0.70) | SIRT3NR1H4PTPN1KDM5AKDM7A | |
| SCHEMBL3973517 | 0.80 | PTPN1 (0.66) | SIRT3NR1H4PTPN1KDM5AKDM7A | |
| SCHEMBL5987679 | 0.80 | NR1H4 (0.43) | SIRT3NR1H4PTPN1KDM5AKDM7A | |
| SCHEMBL5413893 | 0.79 | PTPN1 (0.63) | NR1H4PTPN1KDM5AKDM7A | |
| SCHEMBL7336051 | 0.79 | PTPN1 (0.65) | SIRT3NR1H4PTPN1KDM5AKDM7A | |
| SCHEMBL3972255 | 0.78 | PTPN1 (0.55) | SIRT3NR1H4PTPN1KDM5AKDM7A | |
| SCHEMBL5987451 | 0.78 | SIRT3 (0.54) | SIRT3NR1H4PTPN1KDM5AKDM7A | |
| SCHEMBL4674317 | 0.77 | NR1H4 (0.49) | SIRT3NR1H4PTPN1KDM5AKDM7A | |
| SCHEMBL4673205 | 0.76 | NR1H4 (0.40) | SIRT3NR1H4PTPN1KDM5AKDM7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7534894-B2 | Biphenyloxy-acids | WYETH (US) | 2009-05-19 | — | — | US | claimed |
| US-20060020003-A1 | Biphenyloxy-acids | WYETH (US) | 2006-01-26 | — | — | US | claimed |
| US-7534894-B2 | Biphenyloxy-acids | WYETH (US) | 2009-05-19 | — | — | US | disclosed |
| EP-1667959-A1 | BIPHENYLOXY-ACIDS | Wyeth (US) | 2006-06-14 | — | — | EP | disclosed |
| US-20060020003-A1 | Biphenyloxy-acids | WYETH (US) | 2006-01-26 | — | — | US | disclosed |
| WO-2005030702-A1 | BIPHENYLOXY-ACIDS | WYETH (US) | 2005-04-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060020003-A1 | Biphenyloxy-acids | AHR, ARNT, NR1H4 | SIRT3 2700/4885NR1H4 3/4885PTPN1 1495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.