Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | DPYD | Q12882 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thymine SCHEMBL211722 | 0.89 | ATAD2 (0.70) | ATAD2GAADPYDLMNAALDH1A1 | |
| Thymine SCHEMBL3972000 | 0.88 | ATAD2 (0.56) | ATAD2GAADPYDLMNAALDH1A1 | |
| Thymine SCHEMBL3364510 | 0.81 | ATAD2 (0.79) | ATAD2GAADPYDLMNAALDH1A1 | |
| Thymine SCHEMBL4349014 | 0.81 | ATAD2 (0.79) | ATAD2GAADPYDLMNAALDH1A1 | |
| Thymine SCHEMBL188134 | 0.81 | ATAD2 (0.79) | ATAD2GAADPYDLMNAALDH1A1 | |
| Thymine SCHEMBL1452487 | 0.81 | ATAD2 (0.79) | ATAD2GAADPYDLMNAALDH1A1 | |
| Thymine SCHEMBL28570793 | 0.79 | ATAD2 (0.76) | ATAD2GAADPYDLMNAALDH1A1 | |
| Thymine SCHEMBL28575361 | 0.79 | ATAD2 (0.76) | ATAD2GAADPYDLMNAALDH1A1 | |
| Thymine SCHEMBL6911382 | 0.77 | ATAD2 (0.73) | ATAD2GAADPYDLMNAALDH1A1 | |
| Thymine SCHEMBL8304490 | 0.77 | ATAD2 (0.86) | ATAD2GAADPYDLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009052050-A1 | DIOXOLANE THYMINE PHOSPHORAMIDATES AS ANTI-HIV AGENTS | PHARMASSET, INC. (US) | 2009-04-23 | — | — | WO | disclosed |
| WO-2009052050-A1 | DIOXOLANE THYMINE PHOSPHORAMIDATES AS ANTI-HIV AGENTS | PHARMASSET, INC. (US) | 2009-04-23 | — | — | WO | disclosed |
| US-20090099136-A1 | DIOXOLANE THYMINE PHOSPHORAMIDATES AS ANTI-HIV AGENTS | PHARMASSET, INC. (US) | 2009-04-16 | — | — | US | disclosed |
| US-20090099136-A1 | DIOXOLANE THYMINE PHOSPHORAMIDATES AS ANTI-HIV AGENTS | PHARMASSET, INC. (US) | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099136-A1 | DIOXOLANE THYMINE PHOSPHORAMIDATES AS ANTI-HIV AGENTS | TYMP, DTYMK, TYMS | ATAD2 3904/4885GAA 723/4885DPYD 20/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.