Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21244220 | 0.86 | LMNA (0.51) | LMNAMEN1KMT2ACYP2A6ALDH1A1 | |
| SCHEMBL15619469 | 0.83 | ALDH1A1 (0.53) | LMNAMEN1KMT2ACYP2A6ALDH1A1 | |
| SCHEMBL2093660 | 0.82 | MEN1 (0.56) | LMNAMEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL17796920 | 0.80 | ALDH1A1 (0.52) | MEN1KMT2AALDH1A1L3MBTL1THRA | |
| SCHEMBL9537883 | 0.79 | CYP2A6 (0.47) | LMNAMEN1KMT2ACYP2A6ALDH1A1 | |
| SCHEMBL21933933 | 0.79 | LMNA (0.68) | LMNAMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL15627435 | 0.79 | LCK (0.48) | LMNAMEN1KMT2ACYP2A6ALDH1A1 | |
| SCHEMBL3911337 | 0.79 | HTT (0.51) | LMNAMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL3904432 | 0.78 | CAMK2A (0.44) | LMNAMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL11158773 | 0.78 | PLK1 (0.55) | LMNAMEN1KMT2AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029026-A1 | NOVEL BIPHENYL DERIVATIVE AND METHOD FOR PREPARING SAME | Dong-A ST Co., Ltd. (KR) | 2016-06-08 | — | — | EP | claimed |
| EP-1711183-A4 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LTD (GB) | 2009-04-01 | — | — | EP | claimed |
| EP-1711183-A2 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2006-10-18 | — | — | EP | claimed |
| WO-2005067537-A2 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2005-07-28 | — | — | WO | claimed |
| EP-2897938-B1 | FLUOROALKYL DIBENZODIAZEPINONE COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2017-03-15 | — | — | EP | disclosed |
| US-9133126-B2 | Fluoroalkyl dibenzoazepinone compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-09-15 | — | — | US | disclosed |